Colon Cancer Screening: What Are the Options?

By Stacy Simon No one looks forward to a colonoscopy, or the bowel prep that goes with it. But colon screening – testing to look for cancer before symptoms start – helps saves lives. Screening can find colon cancer early when it’s small and easier to treat, or even prevent it altogether. Colonoscopy, however, is just one of many tests that can be used to look for colon cancer. And doctors and researchers continue to develop new ones. Stool DNA test RESOURCES: How the American Cancer Society Fights Colon CancerColon Cancer Stories of Hope American Cancer Society screening guidelines More information about colon cancer A new type of non-invasive test to check for colon cancer is available now, and may appeal to people who want to be screened, but don’t want to undergo the usual preparation required for a colonoscopy and some other screening tests. It’s called a stool DNA test because it looks for certain gene changes that are sometimes found in colon cancer cells. The FDA approved a stool DNA test called Cologuard in 2014. The patient uses a kit at home to collect a stool sample and mail it to a lab. The test checks for DNA changes that could be a sign of cancer or pre-cancerous growths called polyps. It also checks for blood in the stool, which can be a sign of cancer. No special diet or bowel preparation (no laxatives or enemas) are required for a stool DNA test. However, if the Cologuard test does show a possible cancer or pre-...
Source: American Cancer Society :: News and Features - Category: Cancer & Oncology Tags: Colon/Rectum Cancer Prevention/Early Detection Source Type: news

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Publication date: Available online 15 June 2019Source: MethodsAuthor(s): Rui Yan, Fei Ren, Zihao Wang, Lihua Wang, Tong Zhang, Yudong Liu, Xiaosong Rao, Chunhou Zheng, Fa ZhangAbstractEven with the rapid advances in medical sciences, histopathological diagnosis is still considered the gold standard in diagnosing cancer. However, the complexity of histopathological images and the dramatic increase in workload make this task time consuming, and the results may be subject to pathologist subjectivity. Therefore, the development of automatic and precise histopathological image analysis methods is essential for the field. In thi...
Source: Methods - Category: Molecular Biology Source Type: research
Publication date: Available online 15 June 2019Source: Journal of Molecular LiquidsAuthor(s): Prakash Bansode, Pradnya Patil, Prafulla Choudhari, Manish Bhatia, Apurva Birajdar, Indumathi Somasundaram, Gajanan RashinkarAbstractA novel series of ferrocene tethered ionic liquids (ILs) has been synthesized by quaternization of 1-N-(ferrocenylmethyl)benzimidazole, 1-N-(ferrocenylmethyl)imidazole and 1-N-(ferrocenylmethyl)-1,2,4-triazole with long chain alkyl bromides. The synthesized ILs were screened for their anticancer activity against human breast cancer cell line MCF-7. ILs 2a–d and 4b displayed significant anticanc...
Source: Journal of Molecular Liquids - Category: Molecular Biology Source Type: research
In this study, whole genome comparative genomic hybridization array (array CGH) based genomic analysis was performed on twelve Saudi Lynch syndrome patients. A total of 124 chromosomal alterations (structural loss) were identified at mean log2 ratio cut off value of ±0.25. We also found structural loss in 2p21-p16.3, 3p23-p14.2, 7p22.1 and 1p34.1-p33 regions. These findings were subsequently validated by real time quantitative PCR showing downregulation of MSH2, MSH6, EPCAM, MLH1, PMS2 and MUTYH genes. These findings shall help in establishing database for alterations in mismatch repair genes underlying Lynch syndro...
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
Publication date: 1 September 2019Source: Colloids and Surfaces B: Biointerfaces, Volume 181Author(s): David Limón, Kirian Talló Domínguez, María Luisa Garduño-Ramírez, Berenice Andrade, Ana C. Calpena, Lluïsa Pérez-GarcíaAbstractSupramolecular hydrogels were synthesized using a bis-imidazolium based amphiphile, and incorporating chemically diverse drugs, such as the cytostatics gemcitabine hydrochloride and methotrexate sodium salt, the immunosuppressive drug tacrolimus, as well as the corticoid drugs betamethasone 17-valerate and triamcinolone acetonide, and th...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Chammari Pothipor, Natta Wiriyakun, Thitirat Putnin, Aroonsri Ngamaroonchote, Jaroon Jakmunee, Kontad Ounnunkad, Rawiwan Laocharoensuk, Noppadol AroonyadetAbstractRecent studies show that electrochemical biosensors offer simple, robust and low-cost solution for point-of-care applications. To meet rigorous requirements of early disease diagnosis and other medical applications, nanomaterials have been investigated to increase sensitivity and selectivity of electrochemical sensors. Herein, we successfully developed graphene-poly(3-...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
In this study, we employed an efficient strategy by the combinations of chain-growth condensation polymerization (CGCP), styrenics-assisted atom transfer radical coupling (SA ATRC), and ring-opening polymerization (ROP) to synthesize novel miktoarm (μ) star copolymers. Accordingly, poly(N-octyl benzamide) (PBA) and poly(ε-caprolactone) (PCL) arms were conjugated to form μ-(PBA)2(PCL)m star (m = ca. 4; Mn = ca. 13400; Đ = 1.17; abbr.: μ-(PBA)(PCL)). Thermal properties of homopolymers and μ-(PBA)(PCL) were examined by thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC...
Source: Polymer - Category: Chemistry Source Type: research
Algorithms, datasets, machine learning, deep learning, cognitive computing, big data, and artificial intelligence: IT expressions that took over the language of 21st-century healthcare with surprising force. If medical professionals want to get ahead of the curve, they rather get familiarized with the basics of A.I. and have an idea of what medical problems they aim to solve. So, let’s take a closer look at machine learning and deep learning in medicine. The ante-room of artificial intelligence The term “artificial intelligence” might be misleading as due to the overuse of the expression, its meanin...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Artificial Intelligence in Medicine Future of Medicine AI algorithm deep learning Health Healthcare Innovation machine learning smart smart algorithm smart health technology Source Type: blogs
Abstract Consumption of traditional fermented dairy products (tFDP) in Africa leads to the ingestion of up to 10(8)Streptococcus infantarius subspecies infantarius (Sii) per millilitre of spontaneously fermented milk. Sii is a member of the Streptococcus bovis/Streptococcus equinus complex (SBSEC) for which some members are associated particularly with colorectal cancer or endocarditis. The extent of health risk to consumers is largely unknown. A hospital-based unmatched case-control study was conducted at Kenyatta National Hospital, Nairobi (Kenya) on 80 cases and 193 controls that were selected exhaustively from...
Source: Acta Tropica - Category: Infectious Diseases Authors: Tags: Acta Trop Source Type: research
Whee! Time for a Tube Up Your Tuchus!image:wikimedia commonsBy Crabby McSlackerSo, some perspective here: for people with serious illnesses who've been through hardcore, painful, debilitating, invasive medical procedures? A colonoscopy is probably child's play. (Although let's be clear, that's just an expression. If your child actually plays this way? We need to talk).But for most people, there's at least a little trepidation. And for many, if statistics are to be believed, that fear is significant enough to skip the procedure entirely! Well sure, it could save your life and all, but really? Do you have to?There are actual...
Source: Cranky Fitness - Category: Consumer Health News Authors: Source Type: blogs
By Stacy Simon Many of the symptoms of colon cancer can also be caused by something that isn’t cancer, such as infection, hemorrhoids, irritable bowel syndrome, or inflammatory bowel disease. In most cases, people who have these symptoms do not have cancer. Still, if you have any of these problems, it is a sign that you should go to the doctor so the cause can be found and treated, if needed:A change in bowel habits, such as diarrhea, constipation, or narrowing of the stool, that lasts for more than a few daysA feeling that you need to have a bowel movement that is not relieved by doing soRectal bleedingDark stools, ...
Source: American Cancer Society :: News and Features - Category: Cancer & Oncology Tags: Colon/Rectum Cancer Prevention/Early Detection Source Type: news
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