Breast Cancer Risk in Childhood Cancer Survivors Without a History of Chest Radiotherapy: A Report From the Childhood Cancer Survivor Study [Pediatric Oncology]
Conclusions
Women not exposed to chest radiotherapy who survive childhood sarcoma or leukemia have an increased risk of breast cancer at a young age. The data suggest high-dose alkylator and anthracycline chemotherapy increase the risk of breast cancer. This may suggest a possible underlying gene-environment interaction that warrants further study.
Source: Journal of Clinical Oncology - Category: Cancer & Oncology Authors: Henderson, Moskowitz, Chou, Bradbury, Neglia, Dang, Onel, Novetsky Friedman, Bhatia, Strong, Stovall, Kenney, Barnea, Lorenzi, Hammond, Leisenring, Robison, Armstrong, Diller, Oeffinger Tags: Epidemiology, Long Term Survival & Late Effects, Outcomes Research Pediatric Oncology Source Type: research
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