Young adults with cystic fibrosis have altered trabecular microstructure by ITS-based morphological analysis

Conclusions Young adults with CF have compromised plate-like and axially aligned trabecular morphology and reduced connectivity between trabeculae. ITS analysis provides unique information about bone integrity, and these trabecular deficits may help explain the increased fracture risk in adults with CF not accounted for by BMD and/or traditional bone microarchitecture measurements.
Source: Osteoporosis International - Category: Orthopaedics Source Type: research