Prolonged suppression of HBV in mice by a novel antibody that targets a unique epitope on hepatitis B surface antigen

Conclusions
These results provided new insight into understanding the therapeutic role and mechanism of antibody against persistent viral infection. The E6F6-like mAbs may provide a novel immunotherapeutic agent against human chronic HBV infection.

Source: Gut - March 9, 2016 Category: Gastroenterology Authors: Zhang, T.-Y., Yuan, Q., Zhao, J.-H., Zhang, Y.-L., Yuan, L.-Z., Lan, Y., Lo, Y.-C., Sun, C.-P., Wu, C.-R., Zhang, J.-F., Zhang, Y., Cao, J.-L., Guo, X.-R., Liu, X., Mo, X.-B., Luo, W.-X., Cheng, T., Chen, Y.-X., Tao, M.-H., Shih, J. W., Zhao, Q.-J., Zhang Tags: Hepatitis B Hepatology Source Type: research