Diabetes Mellitus Type 2: A Driving Force for Urological Complications

Publication date: Available online 8 March 2016 Source:Trends in Endocrinology & Metabolism Author(s): Rashid K. Sayyid, Neil E. Fleshner Type 2 diabetes mellitus (T2DM) is a growing epidemic associated with many adverse complications. Urological complications of diabetes mellitus in men are gaining recognition. Previously unknown associations between T2DM and risk for prostate cancer, bladder cancer, renal cell carcinomas, urinary tract infections, nephrolithiasis, penile lesions, androgen deficiency, and erectile dysfunction have been discovered. Significantly, metformin could play a role in the management of urological malignancies, and therapies used for management of these cancers could in return lead to increased risk for diabetes. In this review, we aim to bridge the gap between T2DM and urological complications by discussing the latest findings in these fields, with the ultimate goal being improved patient care on both fronts.
Source: Trends in Endocrinology and Metabolism - Category: Endocrinology Source Type: research

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