Summaries: International Kidney Cancer Symposium

Conclusion: there is no increased risk of doing the lymph node dissection early on.   Dr. Eggener-CON   Basics Lymph node dissections rarely done, even for large tumors, because there is no proven therapeutic or staging benefit for low risk patients.  A Mayo study revealed no data showing therapeutic benefit in high risk patients.  For clinically node negative high risk patients, there is staging value but no proven therapeutic benefit. Rate of positive nodes is associated with stage and grade; the higher the stage and grade, the more likely there will be positive nodes.  A tumor> 10 cm with sarcomatoid features and tumor necrosis is also associated with positive nodes. Looking at several studies, the percentage of patients that were found to have positive nodes at the time of surgery was relatively small in all but one study.  The 5-year cancer specific survival for these patients was very consistent at 35-39%. According to the National Comprehensive Cancer Network guidelines for kidney cancer, “Regional lymph node dissection is optional but is recommended for patients with adenopathy on preoperative imaging or palpable/visible adenopathy at time of surgery.” Conclusions: Lymph node dissection for patients with clinical node negative T1-T2 disease is proven not to be necessary Lymph node dissection for patients with clinical node negative T3-T4 disease...
Source: Kidney Cancer Association - Category: Urology & Nephrology Source Type: news

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Source: BMJ Comments - Category: General Medicine Source Type: forums
Source: BMJ Comments - Category: General Medicine Source Type: forums
Fifty years ago, in a golden moment of television comedy shows, Rowan &Martin’s Laugh-In program regularly featured “The Flying Fickle Finger of Fate” award.  Wikipedia says it “recognized actual dubious achievements by public individuals or institutions.” Do a Google search.  You’ll quickly see how popular this award became. Yes, I’m dating myself by going back 50 years.  But mine is the generation that often becomes obsessed with being given “the finger” by doctors for digital rectal exams (DRE) looking for prostate cancer. And it is in that context...
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions Mainstream media Oncology/Hematology Source Type: blogs
CONCLUSION: Combined treatment at extremely low concentration of two agents from natural products, As2O3 and resveratrol, has high potential as a cocktail of anticancer drugs for neuroblastoma. PMID: 30343279 [PubMed - in process]
Source: Genomics Proteomics ... - Category: Genetics & Stem Cells Authors: Tags: Cancer Genomics Proteomics Source Type: research
Warburgia ugandensis Sprague (Family Canellacea) commonly known as Ugandan greenheart or pepper bark tree, is a highly valued medicinal plant in traditional medicine with a broad spectrum of antimicrobial activity whose parts especially the leaves and stem bark have for long been used in the treatment and management of many diseases and health conditions such as stomachache, cough, toothache...
Source: Journal of Medicinal Plants Research - Category: Complementary Medicine Source Type: research
In this study, the ethanolic extracts prepared from fresh and dried leaves, bark, and seed skin of Pra (Elateriospermum tapos Blume.) were tested for their antioxidant activity using a ferric reducing ability of plasma (FRAP) assay. The antiproliferative activi...
Source: Journal of Medicinal Plants Research - Category: Complementary Medicine Source Type: research
While becoming pregnant is generally possible for younger breast cancer patients, researchers believe many women change their minds after treatment.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Source Type: news
Researchers tested whether 2 years of maintenance therapy with olaparib would improve outcomes in advanced ovarian cancer patients.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Source Type: news
Researchers tested whether immunotherapy could be safely used in HIV-positive patients with cancer.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Source Type: news
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