Summaries: International Kidney Cancer Symposium

Conclusion: there is no increased risk of doing the lymph node dissection early on.   Dr. Eggener-CON   Basics Lymph node dissections rarely done, even for large tumors, because there is no proven therapeutic or staging benefit for low risk patients.  A Mayo study revealed no data showing therapeutic benefit in high risk patients.  For clinically node negative high risk patients, there is staging value but no proven therapeutic benefit. Rate of positive nodes is associated with stage and grade; the higher the stage and grade, the more likely there will be positive nodes.  A tumor> 10 cm with sarcomatoid features and tumor necrosis is also associated with positive nodes. Looking at several studies, the percentage of patients that were found to have positive nodes at the time of surgery was relatively small in all but one study.  The 5-year cancer specific survival for these patients was very consistent at 35-39%. According to the National Comprehensive Cancer Network guidelines for kidney cancer, “Regional lymph node dissection is optional but is recommended for patients with adenopathy on preoperative imaging or palpable/visible adenopathy at time of surgery.” Conclusions: Lymph node dissection for patients with clinical node negative T1-T2 disease is proven not to be necessary Lymph node dissection for patients with clinical node negative T3-T4 disease...
Source: Kidney Cancer Association - Category: Urology & Nephrology Source Type: news

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Publication date: 1 December 2018Source: Materials Science and Engineering: C, Volume 93Author(s): Anasuya Roy, Mangala Joshi, B.S. Butola, Sahil MalhotraAbstractWith increasing demand for novel and potent antimicrobial agents to combat cross-infections and infectious diseases, silver and copper based nanoparticles (NPs) deposited over supports such as montmorillonite (MMT) are playing a crucial role in shaping the current research scenario. Although materials based on Ag NP and Cu NP on MMT have been reported, its toxicological properties on human cell lines have not been accounted for. This paper reports a comparative st...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Publication date: Available online 20 August 2018Source: Materials Chemistry and PhysicsAuthor(s): Reza Aghaei, Akbar Eshaghi, Abbas Ali AghaeiAbstractIn this work, hollow SiO2-SiO2 nanocomposite thin film was deposited on a glass substrate by a sol-gel dip-coating method. Transmission electron microscopy (TEM), field emission scanning electron microscopy (FE-SEM) and atomic force microscopy (AFM) were used to investigate the structure and morphology of the nanoparticles and films. Surface wettability and optical properties of the thin films were studied by means of water contact angle analyzer and UV-vis spectrophotometer...
Source: Materials Chemistry and Physics - Category: Materials Science Source Type: research
Publication date: Available online 20 August 2018Source: Biocybernetics and Biomedical EngineeringAuthor(s): R. Sumathi, M. Venkatesuslu, Sridhar P. Arjunan
Source: Biocybernetics and Biomedical Engineering - Category: Biomedical Engineering Source Type: research
Publication date: Available online 20 August 2018Source: NeurocomputingAuthor(s): Junjie Zhang, Yong Xia, Haoyue Zeng, Yanning ZhangAbstractDetection of pulmonary nodules on chest CT is an essential step in the early diagnosis of lung cancer, which is critical for best patient care. In this paper, we propose an automated pulmonary nodule detection algorithm, denoted by NODULe, which jointly uses a conventional method for nodule detection and a deep learning model for genuine nodule identification. Specifically, we first use multi-scale Laplacian of Gaussian (LoG) filters and prior shape and size constraints to detect nodul...
Source: Neurocomputing - Category: Neuroscience Source Type: research
Publication date: Available online 20 August 2018Source: Clinica Chimica ActaAuthor(s): Yonghua Jiang, Juan Ye, Mukun Zhao, Aihua Tan, Haiying Zhang, Yong Gao, Zheng Lu, Chunlei Wu, Yanling Hu, Qiuyan Wang, Xiaobo Yang, Zengnan MoAbstractBackgroundLow testosterone concentrations have been suggested as a risk factor for hypertension, but their contribution to the development of hypertension is not well studied. We carried out a cohort study based on the results of an earlier cross-sectional investigation. We established the association between testosterone concentrations and hypertension.MethodData on 2427 healthy male subj...
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
ConclusionLow PNI predicts poor survival in LC patients.
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
ConclusionsHBcrAg not only can serve as a biomarker to assess HBV loads in patients as well as provide a good method for monitoring cccDNA in HCC, but also can be used as a good prognostic predictor for HCC patients.
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
Resistance training (RT) does not seem to reduce the bone-thinning effects of weight loss in older adults, new research shows.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news
Abstract Reduced peak oxygen uptake (VO2peak) is a common clinical finding in progressive Chagas disease. However, the disease stage in which functional impairment is detectable remains uncertain. The present study compared functional capacity between healthy controls and patients with different clinical forms of Chagas disease. A systematic review and meta-analysis (PROSPERO database CRD42017058353) was conducted following a search of the MEDLINE, Web of Science, CINAHL, and LILACS databases from September to December 2017 for articles published in English, Spanish, or Portuguese, with no date restrictions. We included st...
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
CONCLUSION: We identified a changing pattern of human visceral leishmaniasis occurrence in Ara çatuba: the first period (1999-2009) showed a cyclic pattern, clusters, and presence of spatial dependence in the case point distribution; the second period (2010-2015) showed the lowest rates of all historical series, stable incidence, and cases with a random distribution pattern.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
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