Early Postoperative Nociceptive Threshold and Production of Brain-Derived Neurotrophic Factor Induced by Plantar Incision Are Not Influenced with Minocycline in a Rat: Role of Spinal Microglia.

CONCLUSION: These results suggest that spinal microglia does not contribute substantially to post-incisional nociceptive threshold. The BDNF overexpression response that may contribute to postoperative hyperalgesia and allodynia is likely derived from other sources. PMID: 26939116 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26939116?dopt=Abstract

Source: Neuro-Signals - March 4, 2016 Category: Neurology Authors: Masaki E, Mizuta K, Ohtani N, Kido K Tags: Neurosignals Source Type: research