Increased serum HMGB-1, ICAM-1 and Metalloproteinase-9 levels in Buerger's patients.

CONCLUSION: These data suggest a role for HMGB -1 in the vascular lesions associated with TAO, unveiling HMGB-1 as a potential target for treating this rare disease.
PMID: 26935815 [PubMed - as supplied by publisher]

Source: Current Vascular Pharmacology - March 2, 2016 Category: Drugs & Pharmacology Authors: De Caridi G, Bitto A, Massara M, Pallio G, Pizzino G, Serra R, Altavilla D, Squadrito F, Spinelli F Tags: Curr Vasc Pharmacol Source Type: research