[Research Article] Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability
This study provides proof-of-principle for inducing an MET as differentiation therapy for TICs and uncovers a role for PKA in enforcing and maintaining the epithelial state.
Authors: Diwakar R. Pattabiraman, Brian Bierie, Katharina Isabelle Kober, Prathapan Thiru, Jordan A. Krall, Christina Zill, Ferenc Reinhardt, Wai Leong Tam, Robert A. Weinberg
Source: ScienceNOW - Category: Science Authors: Diwakar R. Pattabiraman Source Type: news
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