Optimizing administrative datasets to examine acute kidney injury in the era of big data: workgroup statement from the 15 th ADQI Consensus Conference

Abstract Purpose of review The purpose of this review is to report how administrative data have been used to study AKI, identify current limitations, and suggest how these data sources might be enhanced to address knowledge gaps in the field. Objectives 1) To review the existing evidence-base on how AKI is coded across administrative datasets, 2) To identify limitations, gaps in knowledge, and major barriers to scientific progress in AKI related to coding in administrative data, 3) To discuss how administrative data for AKI might be enhanced to enable “communication” and “translation” within and across administrative jurisdictions, and 4) To suggest how administrative databases might be configured to inform ‘registry-based’ pragmatic studies. Source of information Literature review of English language articles through PubMed search for relevant AKI literature focusing on the validation of AKI in administrative data or used administrative data to describe the epidemiology of AKI. Setting Acute Dialysis Quality Initiative (ADQI) Consensus Conference September 6-7th, 2015, Banff, Canada Patients Hospitalized patients with AKI Key messages The coding structure for AKI in many administrative datas...
Source: Canadian Journal of Kidney Health and Disease - Category: Urology & Nephrology Source Type: research

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Authors: Chang MS, Chen NC, Hsu CY, Huang CW, Lee PT, Chou KJ, Fang HC, Chen CL Abstract Background: Encapsulating peritoneal sclerosis (EPS) is a serious complication of peritoneal dialysis (PD), with high morbidity and mortality that requires an early diagnosis for effective treatment. PD withdrawal and bacterial peritonitis are important triggers for the onset of EPS. However, few studies have focused on cases of PD withdrawal without a clinical diagnosis of peritonitis, cirrhosis, or carcinomatosis. We aimed to compare the clinical characteristics and computed tomography (CT) images of patients with or without ...
Source: Renal Failure - Category: Urology & Nephrology Tags: Ren Fail Source Type: research
Authors: Refetoff S, Scherberg N, Yuan C, Wu W, Wu Z, McPhaul MJ Abstract Euthyroid individuals with Familial Dysalbuminemic Hyperthyroxinemia (FDH) have often falsely elevated serum free T4 (FT4) concentrations determined by different automated immunoassays. We measured serum FT4 using direct dialysis coupled with tandem mass spectrometry (FT4 DDMS) in individuals with the common albumin gene mutation (ALB R218H) from 14 FDH families and compared to results obtained by direct immunometric assay (FT4 DIMM) and free T4 index (FT4I). While all 14 individuals with FDH had elevated total serum T4, the FT4 measured by D...
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
A woman resigned to dialysis treatments three times a week gets a rare gift when a friend shows up at the hospital and asks, “Will you be my kidney sista?”
Source: WebMD Health - Category: Consumer Health News Source Type: news
Publication date: Available online 13 December 2019Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Yue Shen, Yifeng Wang, Yuanyuan Shi, Xiao Bi, Jingyi Xu, Qiuyu Zhu, Feng DingAbstractAnionic and protein-bound uremic toxins, represented by indoxyl sulfate (IS), may be associated with cardiovascular outcomes and the progression of chronic kidney disease in cases of injured kidney function and are not easily cleared by traditional dialysis therapy. We fabricated cationic liposomes that were modified with polyethyleneimine (PEI), octadecylamine (Oct), and hexadecyl trimethyl ammonium bromide (CTAB), and evaluated the...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
CONCLUSION: This case demonstrates the possibility of arterial compression by an adjacent venous stent graft, especially in a patient with a thin habitus and a brachial-brachial arteriovenous graft. Detailed identification of the outflow vein anatomy before stent implantation is mandatory to avoid such a complication. PMID: 31825299 [PubMed - as supplied by publisher]
Source: The Journal of Vascular Access - Category: Surgery Tags: J Vasc Access Source Type: research
CONCLUSION: Ectopic catheter replacement can improve the primary patency rate and auxiliary primary patency rate of catheters. Ectopic catheter replacement may require sufficient surgical skills with digital subtraction angiography, resulting in a better prognosis. PMID: 31820667 [PubMed - as supplied by publisher]
Source: The Journal of Vascular Access - Category: Surgery Tags: J Vasc Access Source Type: research
THURSDAY, Dec. 12, 2019 -- A proximal radial artery endovascular arteriovenous fistula to allow vascular access in patients who require hemodialysis remains highly functional at two years, according to a study recently published online in the...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Is sildenafil a safe and effective treatment option for preeclampsia in pregnancy? A new review examines the evidence.Nephrology Dialysis Transplantation
Source: Medscape Radiology Headlines - Category: Radiology Tags: Ob/Gyn & Women ' s Health Journal Article Source Type: news
ConclusionsManagement of delivery in cases of suspected autosomal recessive renal polycystic kidney disease needs to be discussed because of the risk of abdominal dystocia. The route and timing of delivery depend on the size of the fetal abdominal circumference and the gestational age. The rate of kidney growth must also be taken into account.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
ConclusionInitiation of eculizumab within 7  days of hospitalisation is associated with lower dialysis rates, less time in ICU, less plasmapheresis, and lower hospitalisation costs compared with late initiation.
Source: PharmacoEconomics - Category: Health Management Source Type: research
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