Metastatic colon neuroendocrine carcinoma found in a patient with ulcerative colitis during annual endoscopic surveillance

A 70-year-old man with a 12-year history of ulcerative colitis (UC) underwent a colonoscopy including chromoendoscopy 1 year earlier. Mild proctosigmoiditis was observed with no malignant findings. Surveillance colonoscopy 12 months later revealed an elevated lesion 15 mm in diameter with a central depression in the sigmoid colon (A). CT scan revealed multiple metastatic lesions in the liver, yet no lesion was found on a CT scan performed 4 months before the last colonoscopy (B). Tumor biopsy specimens from both the colon and liver showed solid/nesting poorly differentiated cells with hyperchromatic nuclei and scanty cytoplasm (C, colon; D, liver).
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: At the focal point Source Type: research