Abstract P5-17-02: Treatment and prognosis of DCIS during twenty years. A population-based register study from a Swedish cohort

The increasing incidence of ductal carcinoma in situ (DCIS) of the breast has been attributed to the wide adoption of mammography screening programmes. The aim of the present study was to analyse trends in incidence, treatment and outcome of DCIS over a 20-year time period in a Swedish health care region, with a source population of two million, based on systemically collected data in a regional Breast Cancer Quality Registry started in 1992.All patients registered with a diagnosis of primary DCIS in the Breast Cancer Quality Registry in the Uppsala-Örebro healthcare region between 1992 and 2012 were included. The study period was divided into four time periods.The registry contains information on tumour characteristics, treatment and follow-up data and is linked to the Swedish cancer registry, to which reporting of all newly diagnosed malignant tumours in Sweden is mandated. To verify the validity of the Breast Cancer Quality Registry, 300 women recorded with a diagnosis of DCIS were randomly selected and their medical records were collected to compare clinical data, treatment data and subsequent breast cancer events compared to registry data. The completeness and reliability of the registration of most key variables were overall good, 91-99%.A total of 2,952 patients with DCIS were registered, of which eight were men. The proportion of DCIS to all diagnosed breast cancers was 9.5%, with no clear increase over time. The majority of the DCIS cases were detected by screening ...
Source: Cancer Research - Category: Cancer & Oncology Authors: Tags: Poster Session Abstracts Source Type: research