Local inhibition of elastase reduces EMILIN1 cleavage reactivating lymphatic vessel function in a mouse lymphedema model

In conclusion, the attempts to locally block EMILIN1 degradation represent the basis for a novel "ECM" pharmacological approach to assess new lymphedema treatments.

Source: Clinical Science - February 26, 2016 Category: Biomedical Science Authors: Pivetta, E., Wassermann, B., Del Bel Belluz, L., Danussi, C., Modica, T. M., Maiorani, O., Bosisio, G., Boccardo, F., Canzonieri, V., Colombatti, A., Spessotto, P. Tags: Translational Science Source Type: research