The heat shock protein 90 inhibitor, 17-AAG, attenuates thioacetamide induced liver fibrosis in mice.

CONCLUSION: The Hsp90 inhibitor, 17-AAG, can attenuate thioacetamide hepatotoxicity through oxidative stress counterbalance, reducing stellate cells activity and inducing apoptosis. PMID: 26922527 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26922527?dopt=Abstract

Source: Pharmacological Reports - February 29, 2016 Category: Drugs & Pharmacology Authors: Abu-Elsaad NM, Serrya MS, El-Karef AM, Ibrahim TM Tags: Pharmacol Rep Source Type: research

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