Ifenprodil for prolonged spinal blockades of motor function and nociception in rats.

CONCLUSIONS: The resulting data demonstrated that ifenprodil produces a dose-dependent local anesthetic effect in spinal anesthesia. Ifenprodil shows a more sensory-selective duration of action over motor block, whereas the duration of anesthesia is significantly longer with ifenprodil than with bupivacaine. PMID: 26922539 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26922539?dopt=Abstract

Source: Pharmacological Reports - February 29, 2016 Category: Drugs & Pharmacology Authors: Chen YW, Chiu CC, Wang JN, Hung CH, Wang JJ Tags: Pharmacol Rep Source Type: research

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