Serum testosterone, testosterone replacement therapy and all‐cause mortality in men with type 2 diabetes: retrospective consideration of the impact of PDE5 inhibitors and statins

ConclusionsTestosterone replacement therapy is independently associated with reduced mortality in men with T2DM. PDE5I use, included as a confounding factor, was associated with decreased mortality in all patients and, those not on TRT, suggesting independence of effect. The impact of PDE5I treatment on mortality (both HR and OR < 0.25) needs confirmation by independent studies.

Source: International Journal of Clinical Practice - February 1, 2016 Category: Internal Medicine Authors: G. Hackett, A. H. Heald, A. Sinclair, P. W. Jones, R. C. Strange, S. Ramachandran Tags: Original Paper Source Type: research