Lycopodium alkaloids from Lycopodium obscurum L. f. strictum

Publication date: March 2016 Source:Phytochemistry Letters, Volume 15 Author(s): Li-Jun Wang, Juan Xiong, Wei Wang, Hai-Yan Zhang, Guo-Xun Yang, Jin-Feng Hu Two new Lycopodium alkaloids, strictumines A (1) and B (2), along with 18 related known compounds were isolated from the whole plant of Lycopodium obscurum L. f. strictum. The structures of the new compounds were established by spectroscopic methods and chemical transformation. This is the first report on chemical constituents of the title plant. All the isolates were evaluated for their inhibitory activity against acetylcholinesterase (AChE), and only a few were found to show slight bioactivity. Graphical abstract

Source: Phytochemistry Letters - February 24, 2016 Category: Chemistry Source Type: research