Oral Steroids, NSAIDs Equally Safe, Effective for Acute GoutOral Steroids, NSAIDs Equally Safe, Effective for Acute Gout

A large, multicenter randomized trial found that oral prednisolone and oral indomethacin were equally effective at reducing acute gout pain in patients presenting to emergency departments. Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Rheumatology News Source Type: news

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Condition:   Gout Interventions:   Drug: DYV700;   Other: Placebo Sponsor:   Dyve Biosciences, Inc. Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractBackgroundPeople with Alzheimer's disease (AD) often have multimorbidity and take multiple medicines. Yet few studies have examined medicine utilization for comorbidities comparing people with and without AD.ObjectiveThe aim was to investigate the patterns of medication use for comorbidities in people with and without AD.MethodsAn Australian population ‐based study was conducted using the Pharmaceutical Benefits Scheme 10% sample of pharmacy claims data.People with ADwere defined as those dispensed medicines for dementia (cholinesterase inhibitors, memantine, or risperidone for behavioral and psychological sympto...
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - Category: Drugs & Pharmacology Authors: Tags: Original Research Article Source Type: research
In 1975, researchers from Yale investigated an epidemic of 51 patients with arthritis who lived near the woodsy town of Lyme, Connecticut. The most common symptom was recurrent attacks of knee swelling. A few had pain in other joints, such as the wrist or ankle. Many had fever, fatigue, and headache. Some remembered a round skin rash before the onset of knee swelling. We now know that Lyme disease is an infection acquired from tick bites, caused by a spiral bacterium named Borrelia burgdorferi. After a tick bite, Borrelia bacteria wriggle through the skin away from the bite site. This leads to a circular red rash, known as...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Arthritis Bones and joints Infectious diseases Source Type: blogs
ConclusionsMost subjects were females and developed calcinosis in adulthood. Small joints (hand and wrist) and the upper limbs were frequently involved. The presence of different phases of pathological features in the same subject suggests that about half of the study participants had been misdiagnosed with another condition (such as gout, osteoarthritis, etc.). Complete surgical excision led to cure without recurrence during follow-up in majority of the study participants.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research
Updated Date: Mon, 16 Sep 2019 00:00:00 EDT
Source: DailyMed Drug Label Updates - Category: Drugs & Pharmacology Source Type: alerts
Our body is flexible due the joints. These joints connect two bones, provide support and help in the body parts movement. Joint pain is a feeling of discomfort, aches and soreness in any of our body ’s joint. There have been lots of cases of people having aches in their joints. These joint pains are due to injuries affecting the ligaments, bursae, or tendons surrounding the joint. Pain in the joints is also due to infection and inflammation and in an extremely rare case because of cancer. It becomes extremely painful when you try to move your body parts suffering this pain.There are different conditions which are res...
Source: radRounds - Category: Radiology Authors: Source Type: blogs
Authors: Pao CH, Ko Y Abstract Objective: To assess the psychometric properties of the Chinese version of the Gout Impact Scale (GIS), a gout-specific HRQoL measure. Methods: This was a one-center, cross-sectional, observational survey of patients with gout recruited from the Taipei Medical University Hospital from November 2017 to April 2018. The respondents were recruited by convenience sampling. The reliability of the Chinese GIS was tested by Cronbach's α coefficient and adjusted using the Spearman-Brown prophecy formula. Content validity was assessed and confirmed by rheumatologists and pharmacists befor...
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
Abstract The present review is aimed at providing a comprehensive summary of the botanical characteristics, ethnomedicinal uses, phytochemical, pharmacological, and toxicological studies of the genus Ajuga L. The extensive literature survey revealed Ajuga L. species to be a group of important medicinal plants used for the ethnomedical treatment of rheumatism, fever, gout, sclerosis, analgesia, inflammation, hypertension, hyperglycemia, joint pain, palsy, amenorrhea, etc., although only a few reports address the clinical use and toxicity of these plants. Currently, more than 280 chemical constituents have been isol...
Source: The American Journal of Chinese Medicine - Category: Complementary Medicine Authors: Tags: Am J Chin Med Source Type: research
Publication date: Available online 14 July 2019Source: Pharmacological ResearchAuthor(s): Federica Raucci, Asif J. Iqbal, Anella Saviano, Paola Minosi, Marialuisa Piccolo, Carlo Irace, Francesco Caso, Raffaele Scarpa, Stefano Pieretti, Nicola Mascolo, Francesco MaioneAbstractGout is a paradigm of acute, self-limiting inflammation caused by the deposition of monosodium urate (MSU) crystals within intra-and/or peri-articular areas, which leads to excruciating pain, joint swelling and stiffness. The infiltration of leukocytes drives the inflammatory response and remains an attractive target for therapeutic intervention. In th...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
NEW YORK (Reuters Health)—Nearly three in 10 patients seeking care at the emergency department (ED) for acute gout will be discharged with a prescription for opioids, new research shows. “Our study suggests a high use of prescription opioid in patients discharged from the ED with a diagnosis of gout, a condition that can be managed... [Read More]
Source: The Rheumatologist - Category: Rheumatology Authors: Tags: Conditions Crystal Arthritis Arthritis Care & Research Emergency Department Gout opioid Pain Pain Management Source Type: research
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