Vascular insufficiency, not inflammation, contributes to chronic gliosis in a rat CNS transplantation model.

CONCLUSION: These data suggest that ischemic conditions and blood brain barrier damage can be a primary mechanism that initiates chronic gliosis and associated inflammatory changes in central nervous system tissue. PMID: 26890100 [PubMed - as supplied by publisher]
Source: Restorative Neurology and Neuroscience - Category: Neurology Tags: Restor Neurol Neurosci Source Type: research