The usefulness of determining the presence of BRAF V600E mutation in fine-needle aspiration cytology in indeterminate cytological results.

CONCLUSIONS: The presence of BRAF V600E mutation in FNAC material is always associated with the presence of TC. The usefulness of determining the presence of BRAF V600E in FNAC in cytological groups 3 and 4 is associated with low sensitivity in the diagnosis of thyroid cancer. Due to its high specificity BRAF V600E study may be useful in determining the scope of surgery in patients in cytological group 5. (Endokrynol Pol 2016; 67 (1): 41-47).
PMID: 26884114 [PubMed - in process]

Source: Endokrynologia Polska - February 19, 2016 Category: Endocrinology Authors: Kowalska A, Kowalik A, Pałyga I, Walczyk A, Gąsior-Perczak D, Kopczyński J, Lizis-Kolus K, Szyska-Skrobot D, Hurej S, Radowicz-Chil A, Chodurska R, Wypiórkiewicz E, Chłopek M, Nowak E, Niemyska K, Góźdź S Tags: Endokrynol Pol Source Type: research