Angiotensin Converting Enzyme 2/Ang-(1-7)/Mas Axis Protects Brain from Ischemic Injury with a Tendency of Age-dependence.

CONCLUSIONS: Angiotensin converting enzyme 2/Ang-(1-7)/Mas axis protects brain from ischemic injury via the Nox/ROS signaling pathway, with a greater effect in older animals. PMID: 24581232 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/24581232?dopt=Abstract

Source: CNS Neuroscience and Therapeutics - March 2, 2014 Category: Neuroscience Authors: Zheng JL, Li GZ, Chen SZ, Wang JJ, Olson JE, Xia HJ, Lazartigues E, Zhu YL, Chen YF Tags: CNS Neurosci Ther Source Type: research