Does integration of HIV and SRH services achieve economies of scale and scope in practice? A cost function analysis of the Integra Initiative

Conclusions The results from this analysis reveal that contrary to expectation, efficiency gains from the integration of HIV and SRH services, if any, are likely to be modest. Efficiency gains are likely to be most achievable in settings that are currently delivering HIV and SRH services at a low scale with high levels of fixed costs. The presence of cost complementarities for only three service combinations implies that careful consideration of setting-specific clinical practices and the extent to which they can be combined should be made when deciding which services to integrate. Trial registration number NCT01694862.
Source: Sexually Transmitted Infections - Category: Sexual Medicine Authors: Tags: Health policy, Open access, Drugs: infectious diseases, HIV/AIDS, Cervical cancer, Cervical screening, Contraception, Family planning, Gynecological cancer, Screening (oncology), HIV / AIDS, HIV infections, Vulvovaginal disorders, Screening (epidemiology) Source Type: research

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In this study we explored the use of a natural compound rubusoside (RUB) as a solubilizer to enhance the solubility of a fluorescence-labeled C6-Ceramide (NBD C6-Ceramide) and to characterize its pharmacokinetics and tissue distribution in an animal model. RUB significantly enhanced the solubility of NBD C6-Ceramide by forming nanomicelles, and efficiently delivered NBD C6-Ceramide in rats by oral and intravenous administration. RUB loaded 1.96% of NBD C6-Ceramide in the nanomicelles and solubilized it to a concentration of 3.6 mg/mL in water. NBD C6-Ceramide in nanomicelles remained stable in aqueous solutions, all...
Source: Prostaglandins and Other Lipid Mediators - Category: Lipidology Source Type: research
Publication date: Available online 10 December 2019Source: Journal of Food Composition and AnalysisAuthor(s): Afsaneh Mohajer, Abbas Norouzian Baghani, Parisa Sadighara, Kiandokht Ghanati, Shahrokh NazmaraAbstractIn this current study, the contents of heavy metals including Pb, As, Cr, Cd, Zn, Cu, and Mn in imported rice bran oil in Iran were investigated with microwave digestion method based on an inductively coupled plasma optical emission spectrometry system (ICP-OES). The concentrations range of Pb, Cr, Cd, As, Zn, and Cu in rice bran oil samples were measured as 0.066 - 0.30, 0.008 - 0.014, 0.005 - 0.01, 0.047- 0.01, ...
Source: Journal of Food Composition and Analysis - Category: Food Science Source Type: research
Authors: Hill BG, Shiva S, Ballinger S, Zhang J, Darley-Usmar VM Abstract It is now becoming clear that human metabolism is extremely plastic and varies substantially between healthy individuals. Understanding the biochemistry that underlies this physiology will enable personalized clinical interventions related to metabolism. Mitochondrial quality control and the detailed mechanisms of mitochondrial energy generation are central to understanding susceptibility to pathologies associated with aging including cancer, cardiac and neurodegenerative diseases. A precision medicine approach is also needed to evaluate the ...
Source: Biological Chemistry - Category: Chemistry Tags: Biol Chem Source Type: research
July 23, 2018A simple procedure is lowering the risk for thousands of couples in  Tanzania.Twenty-one-year-old Khadija Butemi was doing her morning chores when she heard an announcement through a loudspeaker passing by on the nearby country road.There was a campaign going on, it said, for men who wanted to undergo voluntary medical male circumcision (VMMC). She immediately thought of her husband, a 22-year-old fisherman, who was down by the lake fishing.The couple lives with their two-year-old daughter in Nansio, a remote village on the island of Ukerewe, Tanzania. VMMC isn ’t routinely offered in the area, and ...
Source: IntraHealth International - Category: International Medicine & Public Health Authors: Source Type: news
By Susan Blumenthal, M.D. and Alexandrea Adams The recent commemoration of National Women’s Health Week provided an important time to mark the progress that has been made in advancing women’s health over the past two decades and to highlight what more needs to be done to achieve women’s health equity in America. Historically, women have experienced discrimination in health care despite making 80 percent of health care decisions for their families, using more medical services than men, and suffering greater disability from chronic disease. Before the mid 1990’s, women were often excluded as subjects ...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
Funding Opportunity ID: 287641 Opportunity Number: CDC-RFA-GH11-11500503SUPP16 Opportunity Title: Program Expansion Supplement: Provision of Male Medical Circumcision (MMC) in South Africa under PEPFAROpportunity Category: DiscretionaryOpportunity Category Explanation: Funding Instrument Type: Cooperative AgreementCategory of Funding Activity: HealthCategory Explanation: CFDA Number(s): 93.067Eligible Applicants: Others (see text field entitled "Additional Information on Eligibility" for clarification)Additional Information on Eligibility: The eligible entities for this announcement are listed below: Sout...
Source: Grants.gov - Category: Research Tags: Health Source Type: funding
Funding Opportunity ID: 287592 Opportunity Number: CDC-RFA-GH15-15370201SUPP16 Opportunity Title: Program Expansion Supplement: Technical Assistance to Provide High-Quality Voluntary Medical Male Circumcision (VMMC) Services to Programs Supported by the President's Emergency Plan for AIDS Relief (PEPFAR)Opportunity Category: DiscretionaryOpportunity Category Explanation: Funding Instrument Type: Cooperative AgreementCategory of Funding Activity: HealthCategory Explanation: CFDA Number(s): 93.067Eligible Applicants: Others (see text field entitled "Additional Information on Eligibility" for clarification)A...
Source: Grants.gov - Category: Research Tags: Health Source Type: funding
Funding Opportunity ID: 286885 Opportunity Number: CDC-RFA-GH11-11100501SUPP16 Opportunity Title: Program Expansion Supplement: Supporting Health Worker Staffing in South Africa under PEPFAROpportunity Category: DiscretionaryOpportunity Category Explanation: Funding Instrument Type: Cooperative AgreementCategory of Funding Activity: HealthCategory Explanation: CFDA Number(s): 93.067Eligible Applicants: Others (see text field entitled "Additional Information on Eligibility" for clarification)Additional Information on Eligibility: Eligible applicants that can apply for this funding opportunity are listed be...
Source: Grants.gov - Category: Research Tags: Health Source Type: funding
Anogenital preinvasive and invasive lesions are known to have been on the increase in the industrialised world since the 1970s.1 The increase in anal squamous cell carcinomas and Kaposi's sarcomas (KS) has often been associated with the HIV epidemic, especially among men having sex with men. KS and non-Hodgkin's lymphoma are virus-related (KS-associated herpes virus and Epstein–Barr, respectively) AIDS-defining illnesses.2 Among anogenital cancers, only cervical cancer is listed as AIDS-defining illness. A large proportion of anogenital preinvasive and invasive lesions are human papillomavirus (HPV)-related, with a v...
Source: Sexually Transmitted Infections - Category: Sexual Medicine Authors: Tags: Letter Source Type: research
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