Transplantation: Reverse chimerism enables graft acceptance

Nature Reviews Nephrology 12, 125 (2016). doi:10.1038/nrneph.2016.8 Author: Ellen F. Carney Induction of reverse chimerism in renal allografts by mobilizing host stem cells from the bone marrow enables long-term graft acceptance in animal models, say Zhaoli Sun and colleagues. These researchers previously showed that the CXCR4 antagonist AMD3100 and low-dose tacrolimus act synergistically to mobilize autochthonous
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Research Highlight Source Type: research