Interleukin-17 is a critical target for the treatment of ankylosing enthesitis and psoriasis-like dermatitis in mice.

In conclusion, IL-17 is a key mediator in the pathogenic process of tarsal ankylosis and psoriasis-like dermatitis in male DBA/1 mice caged together. Thus, IL-17 is a potential therapeutic target in ankylosing enthesitis and psoriasis in humans. PMID: 25352178 [PubMed - indexed for MEDLINE]
Source: Autoimmunity - Category: Allergy & Immunology Tags: Autoimmunity Source Type: research