We want access to safe and effective Avastin. Here’s a solution.

Recently, two states in India halted all use of Avastin for the treatment of eye disease following the report of 15 patients who underwent emergency surgery for potentially blinding infections at the C.H. Nagri Municipal Eye Hospital in Ahmedabad.  Though further investigations are ongoing, there is worry that the cluster of infections centered around a tainted lot of compounded Avastin. This most recent event serves as a reminder of the risk that we take every time we inject Avastin into our patients eye. Recent cluster infections have led to greater oversight:  A good thing. In the U.S., great measures have been taken to prevent infection since the 2011 report of two clusters of infections seen in Florida and Tennessee stemming from a single compounding pharmacy in Southern Florida affecting 12 patients.  Weeks later, another tainted lot of Avastin infected patients at the VA hospital in Los Angeles blinding another 5 patients.  Since these episodes, stricter regulations on the compounding and surveillance for infection prior to the distribution of Avastin have virtually eliminated these cluster infections. Moreover, the American Academy of Ophthalmology, the American Society of Retinal Specialists, as well as the Pharmacy Compounding Accreditation Board have done a superb job in organizing providers and pharmacists to report adverse events and educating them on safer practices to reduce infection.  Nevertheless, the Florida, Tennessee, Califor...
Source: Kevin, M.D. - Medical Weblog - Category: Journals (General) Authors: Tags: Conditions Medications Surgery Source Type: blogs

Related Links:

Allostasis and allostatic load are new concepts explaining the changes in body stemming from chronic stress. These concepts are explained with the assessment of metabolic, cardiovascular, inflammatory, and neuroendocrine systems. Type 2 Diabetes Mellitus (DM) is a chronic disease with the fluctuations in fasting plasma glucose, and also in other various biomarkers and poses a risk forother chronic diseases. The course and duration of the disease, genetic factors, and environmental factors, including nutrition, aggravate these complications. Allostatic load is a multi-system assessment. Individuals’ compliance with th...
Source: Current Nutrition and Food Science - Category: Nutrition Source Type: research
Conclusion: These findings suggest that a pro-inflammatory diet is a risk factor for prostate cancer and also can have the impact on body composition.
Source: Current Nutrition and Food Science - Category: Nutrition Source Type: research
Conclusion: Taken together, AFPE that acts at a low micromolar range against breast cancer cells may be considered as a promising candidate for anticancer therapy.
Source: Current Nutrition and Food Science - Category: Nutrition Source Type: research
Publication date: Available online 11 November 2019Source: Journal of Functional FoodsAuthor(s): Shigenobu Ina, Aya Hamada, Hanae Nakamura, Yusuke Yamaguchi, Hitoshi Kumagai, Hitomi KumagaiAbstractThe mechanism of the suppressive effect of rice albumin (RA) on postprandial hyperglycemia after glucose loading was investigated. In order to examine if small peptides derived from RA are responsible for prevention of postprandial hyperglycemia, RA was hydrolysed to indigestible high-molecular-weight peptides (HMP) and low-molecular-weight peptides (LMP) by trypsin, HMP and LMP being fractionated by gel-filtration chromatography...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
A national survey of physicians provides insight into the variation in clinical practices regarding the management of pregnant women with subclinical hypothyroidism.Journal of the Endocrine Society
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news
Might plasma steroid profiles have a diagnostic role in the evaluation of subclinical Cushing syndrome?Journal of Clinical Endocrinology &Metabolism
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news
What have we learned about the manifestations and treatment outcomes of MEN1 among children and young adults?Clinical Endocrinology
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news
CONCLUSIONS: The practice of self-medication with analgesics is frequent among patients with chronic pain, which may be due to the underprescription of more potent analgesics, such as opioids. It can also be said that, given the data presented, there is no crisis of recreational opioid use in the studied population. PMID: 31703816 [PubMed - as supplied by publisher]
Source: Revista Brasileira de Anestesiologia - Category: Anesthesiology Tags: Rev Bras Anestesiol Source Type: research
Conclusion This paper summarizes the current findings regarding the anti-colitis activity of plant-derived alkaloids and shows how these alkaloids exhibit significant and beneficial effects in alleviating colonic inflammation. These natural alkaloids are not only promising agents for IBD treatment but are also components for developing new wonder drugs. However, the underlying molecular mechanisms or toxicological evaluation of most plant-derived alkaloids still require much scientific research, and their actual efficacies for IBD patients have not been verified well in field research. Thus, further clinical trials to elu...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Discussion There are numerous microbial communities inhabited in the human body, which is critical to human health. The relationship between human microbiome and diseases received much attention from both medical and bioinformatics community recently. However, traditional methods to detect their association is costly and labor-intensive. Thus, we proposed here a new computational model called NBLPIHMDA to infer potential microbe-disease associations. NBLPIHMDA first combined known microbe-disease associations in HMDAD and the Gaussian interaction profile kernel similarity to construct disease similarity network and microb...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
More News: Academies | Allergy | Avastin | Blogging | Cancer | Cancer & Oncology | Colon Cancer | Colorectal Cancer | Diabetes | Education | Emergency Medicine | Endocrinology | Eyes | Family Physicians | Government | Health | Health Management | Hospital Management | Hospitals | Insulin | Insurance | Insurers | Lucentis | Medicaid | Medicare | Opthalmology | Pain | Pathology | Pharmaceuticals | Politics | Ranibizumab Injection | University of Pennsylvania