Troponin in Cardiovascular Disease Prevention: Updates and Future Direction

Abstract Cardiac troponin has been well described as the preferred biomarker for diagnosis of myocardial infarction due to the high sensitivity and specificity for myocardial injury. Numerous other conditions apart from acute coronary syndrome can also lead to small elevations in troponin levels. However, the use of cTn as prognostic biomarker for the primary assessment of cardiovascular risk in asymptomatic patient has only recently been described. And with the development of newer generations of high-sensitivity cardiac troponin assays that can detect 10-fold lower concentrations of troponin, the potential value cTn in the prevention and management of asymptomatic cardiovascular disease has come to the fore. This review provides an overview of the transition of cardiac troponin as a marker of acute myocardial injury to one that detects sub-clinical injury. Evidence continues to show that high-sensitivity troponin is emerging as one of the most powerful prognostic biomarkers for the assessment of cardiovascular risk in the general population.
Source: Current Atherosclerosis Reports - Category: Cardiology Source Type: research

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In conclusion, we may affirm that there is some lack of knowledge on relations between PD and CVD, however there is sufficient evidence to justify a periodontal treatment to prevent CVD, in fact PD is very prevalent in middle-aged population and can have a significant impact on the cardiovascular function. PMID: 31538457 [PubMed - in process]
Source: Journal of Biological Regulators and Homeostatic Agents - Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research
BACKGROUND: Snake envenomation is associated with serious complications including infections, bleeding and, in rare occasions, thrombosis. Previous work by our group examined the association of snakebite and acute myocardial infarction. In this systematic ...
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Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Analyst, 2019, Accepted Manuscript DOI: 10.1039/C9AN01260E, PaperZiyi Cheng, Rui Wang, Yanlong Xing, Linlu Zhao, Jaebum Choo, Fabiao Yu Cardiac troponin I (cTnI) and creatine kinase –MB (CK–MB) are important diagnostic biomarkers for acute myocardial infarction (AMI). Many efforts have been undertaken to develop highly sensitive detection methods for the... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research
Publication date: October 2019Source: American Journal of Preventive Medicine, Volume 57, Issue 4Author(s):
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
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Publication date: October 2019Source: The Annals of Thoracic Surgery, Volume 108, Issue 4Author(s): Nicolas d’Ostrevy, Adama Sawadogo, Jean Porterie, Vedat Eljezi, Etienne Geoffroy, Lucie Cassagnes, Lionel CamilleriLeft ventricular unloading during extracorporeal life support aims to minimize potential side effects of increased left ventricular afterload. A transaortic catheter vent implanted through a subclavian approach was used in 2 patients. Patient 1 was a 48-year-old man with a recent history of ST-elevation myocardial infarction who developed refractory cardiogenic shock due to severe biventricular dysfunction...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
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Source: International Journal of Angiology - Category: Cardiology Authors: Tags: Review Article Source Type: research
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Source: Quality of Life Research - Category: Health Management Source Type: research
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Source: Wiener Medizinische Wochenschrift - Category: General Medicine Source Type: research
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