FOXO1 Determines PR Isoform Transactivation in Ovarian Cancer Cells

This study indicates FOXO1 as a critical component for progesterone signaling to promote cellular senescence and reveals a novel mechanism for transcription factor control of hormone sensitivity. Mol Cancer Res; 14(2); 141–62. ©2015 AACR.

Source: Molecular Cancer Research - February 14, 2016 Category: Cancer & Oncology Authors: Diep, C. H., Knutson, T. P., Lange, C. A. Tags: Cell Cycle and Senescence Source Type: research