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PodMed: A Medical News Roundup From Johns Hopkins (with audio)

(MedPage Today) -- This week's topics include seafood consumption and Alzheimer's disease, transcranial stimulation for tinnitus, long-term use of marijuana and cognition, and mobile texts for medication adherence
Source: MedPage Today Psychiatry - Category: Psychiatry Source Type: news

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DEMENTIA signs and symptoms include memory loss, confusion and difficulty concentrating. But, you could lower your risk, or even prevent, Alzheimer ’s disease by eating a Mediterranean diet, scientists have claimed.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
AbstractBrain18F-fluorodeoxyglucose positron emission tomography (FDG-PET) has been utilized to monitor disease conversion from amnestic mild cognitive impairment (aMCI) to Alzheimer ’s dementia (AD). However, the conversion patterns of FDG-PET metabolism across studies are not conclusive. We conducted a voxel-wise meta-analysis using Seed-basedd Mapping that included 10 baseline voxel-wise FDG-PET comparisons between 93 aMCI converters and 129 aMCI non-converters from nine longitudinal studies. The most robust and reliable metabolic alterations that predicted conversion from aMCI to AD were localized in the left pos...
Source: Translational Neurodegeneration - Category: Neurology Source Type: research
AbstractThere are several theories regarding the etiologies of Alzheimer disease (AD). Considering that all genes responsible for familial AD are amyloid protein precursor (APP) or APP metabolizing enzymes, surely aberrant APP metabolism is crucial to pathogenesis of AD. BRI2, a type II transmembrane protein, binds APP and inhibits all α, β, and γ pathways of APP proteolysis. Crossing AD model mice with BRI2 transgenic or BRI2 knockout mice confirmed that BRI2 is an anti-Alzheimer gene. Mutations of BRI2 are known to cause rare familial dementias in human. Analysis of knock-in mice harboring the disease mu...
Source: Medical Molecular Morphology - Category: Molecular Biology Source Type: research
DISCUSSION: Contrary to our hypothesis, also AIT-inappropriate prescriptions were associated with clinical utility. Clinical or neuropsychological variables, not taken into account by the AIT criteria, may help further refine criteria for appropriateness. PMID: 29679576 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research
ConclusionsInitial results of DBS studies for diverse neurological disorders are encouraging but larger, controlled, prospective, homogeneous clinical trials are necessary to establish long term safety and effectiveness. The field of neuromodulation continues to evolve and advances in DBS technology, stereotactic techniques, neuroimaging, and DBS programming capabilities are shaping the present and future of DBS research and use in practice.This article is protected by copyright. All rights reserved.
Source: European Journal of Neurology - Category: Neurology Authors: Tags: Reviews Source Type: research
Conclusions Treatment with benzodiazepines and non-opioid analgesics was more frequent in the tinnitus group, whereas the VMH group showed a higher prevalence of hearing loss and treatment with acetylsalicylic acid. The causes of VMH were dementia with Lewy bodies, Alzheimer disease, and focal lesions in the mesencephalon, pons, left temporal lobe, or left claustrum.
Source: Neurologia - Category: Neurology Source Type: research
Conclusions:This is the first case study to report the clinical and neuropathological features of SIS. Larger autopsy samples are needed to systematically identify clinicopathological correlates of SIS to facilitate research on risk factors and preventative strategies (e.g., return-to-play guidelines) to prevent unnecessary fatalities in young athletes.Study Supported by: This work was supported by the National Institute of Neurological Disorders and Stroke (1U01NS086659-01, U01NS093334, R01NS078337, R56NS078337), Department of Defense (W81XWH-13-2-0064), Department of Veterans Affairs, the Veterans Affairs Biorepository (...
Source: Neurology - Category: Neurology Authors: Tags: Neuro Trauma and Sports Neurology II Source Type: research
This article does not include any meta-analysis and aims simply at providing a comprehensive overview of the raw data reported in this field to date, as an aid to researchers.
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
Diminished hearing can quickly isolate a person. It ’s exhausting to focus on the minutia of a conversation just to ensure processing the important points. It takes concentration, focus and considerable energy!By Elaine C PereiraAlzheimer's Reading RoomMy mother, Elizabeth Ward whose story is profiled in my memoirI Will Never Forget, died from Alzheimer ’s in 2011.If the ravages of brain cell gobbling Alzheimer ’s Disease weren’t enough, she was also stone deaf from Meniere’s Disease.How to Listen to an Alzheimer's PatientSubscribe to the Alzheimer's Reading RoomEmail:Meniere ’s is a dis...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: alzheimer care caring for dementia patients at home dementia care dementia help for caregivers family caregiving health HEARING LOSS help alzheimer's help with dementia care Source Type: blogs
If you're one of the more than 20 million Americans who suffer from chronic kidney disease (CKD), your doctor has probably told you there isn't much they can do for you. Mainstream medicine doesn't have a cure for CKD. What they do have is a lot of drugs to treat the symptoms of it. And most of the drugs will leave you worse off than before you started taking them… Like ESAs, which are prescribed to treat anemia caused by chronic kidney disease. These dangerous drugs can cause strokes, heart attacks, blood clots and seizures. And if your kidneys fail, your only options are dialysis or a kidney transplant...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Anti-Aging Source Type: news
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