NADPH oxidase 2 plays a role in experimental corneal neovascularisation

In conclusion, we have demonstrated that Nox2 is implicated in the inflammatory and neovascular response to corneal chemical injury in mice and clearly VEGF is a mediator of this effect. This work raises the possibility that therapies targeting Nox2 may have potential for suppressing corneal neovascularisation and inflammation in humans.

Source: Clinical Science - January 26, 2016 Category: Biomedical Science Authors: Chan, E. C., Van Wijngaarden, P., Chan, E., Ngo, D., Wang, J.-h., Peshavariya, H. M., Dusting, G. J., Liu, G.-S. Tags: PublishAheadOfPrint Source Type: research