A new cycloartane-type triterpene and a new eicosanoic acid ester from fruits of Paullinia pinnata L.

Publication date: March 2016 Source:Phytochemistry Letters, Volume 15 Author(s): Maurice D. Awouafack, Takuya Ito, Pierre Tane, Takeshi Kodama, Masami Tanaka, Yoshinori Asakawa, Hiroyuki Morita A phytochemical study of the MeOH-soluble portion from the CH2Cl2/MeOH extract of the fruits of Paullinia pinnata resulted in the isolation of a new triterpenoid, cyclopinnatol (1), and a new eicosanoic acid ester, paulliniester (2), together with five known compounds including cycloart-22(E)-ene-3β,25-diol (3), cycloartenol (4), β-sitosterol (5), betulonic acid (6) and oleanonic acid (7). The structures of the new compounds were elucidated by spectroscopic analyses (NMR and MS) and comparisons with published data. Cyclopinnatol (1) and the MeOH-soluble portion exhibited significant and weak antibacterial activities against Staphylococcus aureus, with MICs of 32 and 50μg/mL, respectively. Graphical abstract
Source: Phytochemistry Letters - Category: Chemistry Source Type: research