Severe bupropion overdose and ECMO: two great saves

ChaNaWiT/shutterstock.com 3.5 out of 5 stars Two Cases of Refractory Cardiogenic Shock Secondary to Bupropion Successfully Treated with Veno-Arterial Extracorporeal Membrance Oxygenation. Heise CW et al. J Med Toxicol 2016 Feb 8 [Epub Ahead of Print] Abstract This awesome, exciting paper from Banner University Medical Center in Phoenix describes two teenagers with severe bupropion overdose who survived refractory cardiac arrest after veno-arterial extracorporeal membrane oxygenation (VA-ECMO): Case 1: A 15-year-old girl was brought to hospital after ingesting up to 90 150-mg bupropion tablets. She had a seizure en route and arrived with pulseless electrical activity (PEA). Return of spontaneous circulation was achieved after 20 minutes of cardiopulmonary resuscitation. She was sent by air-ambulance to a tertiary hospital with a Medical Toxicology service. During transport, she had recurrent episodes of PEA. At the receiving hospital, the patient had progressive hypoxia and decreased cardiac output with an ejection fraction
Source: The Poison Review - Category: Toxicology Authors: Tags: Medical burpropion ECMO extracorporeal membrane oxygenation Source Type: news

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Nonfatal overdose rates significantly increased for all drug types except benzodiazepines
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Source: Sensors - Category: Biotechnology Authors: Tags: Article Source Type: research
Abstract In 2017, drug overdoses caused 70,237 deaths in the United States, a 9.6% rate increase from 2016 (1). Monitoring nonfatal drug overdoses treated in emergency departments (EDs) is also important to inform community prevention and response activities. Analysis of discharge data provides insights into the prevalence and trends of nonfatal drug overdoses, highlighting opportunities for public health action to prevent overdoses. Using discharge data from the Healthcare Cost and Utilization Project's (HCUP) Nationwide Emergency Department Sample (NEDS), CDC identified nonfatal overdoses for all drugs, all opio...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
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Source: Substance Abuse - Category: Addiction Authors: Source Type: research
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Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
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