HER3 expression is correlated to distally located and low-grade colon cancer.

Conclusion In this explorative, retrospective study, high HER3 expression in colon cancer was associated to distal colon location and low-grade tumor. High HER3 expression was of prognostic value according to DFS in distal colon cancer in univariate and multivariate analysis. We could not find a significant value of HER3 expression with respect to overall survival (OS).
PMID: 26863446 [PubMed - as supplied by publisher]

Source: Acta Oncologica - February 10, 2016 Category: Cancer & Oncology Authors: Lédel F, Stenstedt K, Hallström M, Ragnhammar P, Edler D Tags: Acta Oncol Source Type: research