DT(270-326) , a Truncated Diphtheria Toxin, Increases Blood-Tumor Barrier Permeability by Upregulating the Expression of Caveolin-1.

CONCLUSIONS: DT(270-326) might provide a novel strategy to increase the delivery of macromolecular therapeutic agents across the BTB. PMID: 26861687 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26861687?dopt=Abstract

Source: CNS Neuroscience and Therapeutics - February 10, 2016 Category: Neuroscience Authors: Lin Y, Wang P, Liu YH, Shang XL, Chen LY, Xue YX Tags: CNS Neurosci Ther Source Type: research