The Myth of Male Menopause
By John Swartzberg, M.D. It's been dubbed "manopause" or "andropause" -- a midlife change for men that some claim is just like menopause for women. But there's no such thing. "Male menopause" is a creation of the pharmaceutical and supplement industries, along with unscrupulous or uninformed practitioners who feel that some of their potency -- sexual and otherwise -- is declining. It sounds perfectly reasonable at first, but scientifically speaking, there's no evidence that men go through menopause in the same way that women do. That's not to say that men's testosterone levels don't decline with age, just as women's estrogen levels do. But there is no abrupt change, no dramatic drop in testosterone for men at midlife like the hormonal decline that occurs when a woman reaches menopause. In fact, your testosterone levels have probably been slowly declining for quite some time, a decline that usually begins around age 30. But many men at midlife are convinced by the messages of pharmaceutical and supplement makers, and so-called "anti-aging doctors," that male menopause is the culprit behind their declining libido and difficulty getting an erection. They make dramatic claims about the effectiveness of testosterone replacement therapy--claims that simply aren't supported by sound medical evidence. The fact is that we don't know if a declining testosterone level is pathological--there's no evidence that it is--or something that is healthy...
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Fabio Penna, Riccardo Ballar ò, Marc Beltrà, Serena De Lucia, Lorena García Castillo, Paola Costelli
Publication date: Available online 18 February 2019Source: Biochimica et Biophysica Acta (BBA) - Molecular Cell ResearchAuthor(s): Kohji Yamada, Kiyotsugu YoshidaAbstractAll organisms end with their death, and many parts of cells die through intrinsic suicide machineries in response to diverse stimuli. These intrinsic cell death pathways are often termed as programmed cell deaths (PCDs), and are critical for organism development, tissue homeostasis and various diseases. Recent evidence has revealed that most of PCDs involve a tumor suppressor p53 and components of the intra-mitochondria. Furthermore, the movement and posit...
People with a history of smoking have less effective immune system, study at University of Leeds showed. Researchers stressed the importance of quitting after a diagnosis.
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Jessica Kang, Chia-Hsiung Liu, Chien-Nan Lee, Hung-Yuan Li, Chien-Wen Yang, Shu-Chien Huang, Shin-Yu Lin, Tzuu-Shuh Jou
Liang Cheng, He Zhuang, Shuo Yang, Huijie Jiang, Song Wang, Jun Zhang
Conclusions: Our data showed that PAA with TAZ/PIPC with a shorter duration PAA (48 h) might be recommended for RC with urinary diversion. We found that the surgical time was significantly shorter in the non-infection group. A prospective study based on our data is desirable to establish or revise PAA strategy for prophylactic medication to prevent postoperative infection after RC with urinary diversion.Urol Int
The aim of this study was to identify the different school refusal behavior profiles and to determine whether these profiles differ from one another based on four situational factors, three response systems and the total score on school anxiety. 1113 Spani...
This longitudinal study explored the relations between fear-enhancing parenting behaviors (modeling and threat information transmission) and children's cognitive biases and anxiety symptoms on three subsequent time points over a one-year period. Participan...
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