Giant primary synovial sarcoma of the anterior mediastinum: A case report and review of literature
We present a case of primary monophasic synovial sarcoma of the anterior mediastinum, in a 22-year-old Nigerian lady who presented with cough, chest pain, and pleural effusion. Chest X-ray (CXR) and computed tomography on admission showed a left-sided huge mass in the left anterior mediastinum with no metastasis to the contralateral pleural cavity. Complete resection of the mediastinal tumor was done and histologic and immunohistochemical analyses confirmed a diagnosis of monophasic synovial sarcoma. However, 10 months postoperation she represented with chest pain, productive cough and a repeat CXR showed multiple left pulmonary nodules. She received two cycles of docetaxel and gemcitabine chemotherapy, but declined further treatment until her demise 8 months later.
Publication date: Available online 30 May 2020Source: Journal of Clinical Orthopaedics and TraumaAuthor(s): Raja Bhaskara Rajasekaran, Duncan Whitwell, Thomas Daniel Arthur Cosker, Christopher Leonard Max Gibbons
Publication date: Available online 30 May 2020Source: Gynecologic Oncology ReportsAuthor(s): Shaina Sedighim, Jonathan Burke, Douglas Schneider, Talia Kamdjou, Julio A. Diaz-Perez, Jonathan Trent, Mecker Möller
Publication date: Available online 30 May 2020Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Alessandra Graziottin, Filippo Murina, Dania Gambini, Stefania Taraborrelli, Barbara Gardella, Maria Campo, the VuNet Study Group
Publication date: Available online 30 May 2020Source: BurnsAuthor(s): Gopal Nambi S, Walid Kamal Abdelbasset
Publication date: June 2020Source: American Journal of Orthodontics and Dentofacial Orthopedics, Volume 157, Issue 6Author(s): Jin-Ho Park, Chung-Ju Hwang, Yoon-Jeong Choi, Khosrow Siamak Houschyar, Jae-Hun Yu, So-Yeon Bae, Jung-Yul Cha
Publication date: Available online 30 May 2020Source: EXPLOREAuthor(s): Bihter Akin, Birsen Karaca Saydam
Pembrolizumab outperformed chemotherapy in patients with microsatellite-instability high/mismatch repair-deficient metastatic colorectal cancer in the KEYNOTE-177 study.Medscape Medical News
LK Rajeev, Rajesh Patidar, Govind Babu, MC Suresh Babu, KN Lokesh, Geeta V Patil OkalyLung India 2017 34(6):545-547Synovial sarcoma of lung is a very rare tumor accounting for 0.5% of all primary lung malignancy. It presents clinically with cough, chest pain, shortness of breath, or hemoptysis, with a mass lesion on X-ray and computerized tomography scan. Diagnosis is made by histopathology and immunohistochemistry. Here, we report a case of 48-year-old male, who presented with right-sided chest pain, cough with blood-tinged sputum, and found to have primary pulmonary synovial sarcoma of lung.
CONCLUSION: A number of symptoms are common across STS subtypes and may form a single STS symptom inventory. PMID: 28588396 [PubMed - in process]
Conclusions: Primary sarcomas of the lung are rare and aggressive tumors.Complete surgical resection with free margins, and chemotherapy increase the survival.