Chemical profiles of human brain tumors by DESI-MS [Medical Sciences]

Examination of tissue sections using desorption electrospray ionization (DESI)-MS revealed phospholipid-derived signals that differ between gray matter, white matter, gliomas, meningiomas, and pituitary tumors, allowing their ready discrimination by multivariate statistics. A set of lower mass signals, some corresponding to oncometabolites, including 2-hydroxyglutaric acid and N-acetyl-aspartic acid, was also observed...

Source: Proceedings of the National Academy of Sciences - February 9, 2016 Category: Science Authors: Jarmusch, A. K., Pirro, V., Baird, Z., Hattab, E. M., Cohen-Gadol, A. A., Cooks, R. G. Tags: Inaugural Articles Physical Sciences Source Type: research