The Neural Basis of Postural Instability Gait Disorder Subtype of Parkinson's Disease: A PET and fMRI Study.

CONCLUSION: The involvement of the caudate, FG, and prefrontal-parietal network may be associated with the prominent gait impairments of PIGD subtype. Our findings expand the pathophysiological knowledge of PIGD subtype and provide valuable information for potential neuromodulation therapies alleviating gait disorders.
PMID: 26842842 [PubMed - as supplied by publisher]

Source: CNS Neuroscience and Therapeutics - February 4, 2016 Category: Neuroscience Authors: Zhang L, Li TN, Yuan YS, Jiang SM, Tong Q, Wang M, Wang JW, Chen HJ, Ding J, Xu QR, Zhang KZ Tags: CNS Neurosci Ther Source Type: research