Nishi Memorial Award in Gastric Cancer
We report 2 elderly female patients with LPE who developed squamous cell carcinoma (SCC). Both underwent laparoscopic ischemic gastric preconditioning followed 2 weeks later by 3-field esophagectomy. Final pathological stages were carcinoma-in-situ and pT3N2, respectively. No adjuvant therapy was given. The patient with in-situ cancer has no evidence of recurrence at 24 months. The 2nd patient opted to follow up locally and died 8 months later. LPE should be closely monitored for malignant degeneration. Esophagectomy should be considered when malignancy is detected.
Conditions: Gastric Cancer; Atrophic Gastritis; Gastric Dysplasia; H.Pylori Infection Interventions: Device: Breath sampling for VOC detection; Procedure: Surgery material collection for VOC headspace analysis; Diagnostic Test: Upper endoscopy; Diagnostic Test: Microbiota testing Sponsors: University of Latvia; Technion, Israel Institute of Technology; University of Ulm; UPPSALA UNIVERSITET; JLM Innovation ...
Conclusions: A simple, convenient, accurate, and robust 2-dimensional liquid chromatography method was developed and verified, which successfully determined the plasma concentrations of apatinib in patients with gastric cancer.
Cancer Gene Therapy, Published online: 16 July 2019; doi:10.1038/s41417-019-0125-7Discovery and validation of methylated-differentially expressed genes in Helicobacter pylori-induced gastric cancer
ConclusionsBoth LI and VI were significant predictors of LN metastasis. The risk of LN metastasis was augmented when both LI and VI were positive. Therefore, LI and VI should be evaluated separately in patients with non-curative endoscopic resection. Additive surgery should be recommended for patients with LI and/or VI.
In conclusion, TTB inhibited OGD/R-induced astrocytes oxidative stress, at least partially through inhibition of HIF1α and VEGF via Nrf2/HO-1 signaling pathway.
This article summarizes the milestones in the development of camrelizumab leading to this first approval for classical Hodgkin lymphoma.
ConclusionsThis case highlights the importance of genetic testing with rare malignancies because the full scope of phenotypic sequelae for known hereditary syndromes has not been mapped.
Condition: Gastric Cancer Intervention: Sponsors: Fundación para la Investigación del Hospital Clínico de Valencia; Instituto Nacional de Cancerologia de Mexico; VU University Medical Center; Pontificia Universidad Catolica de Chile; Vall d'Hebron Institute of Oncology; INSTITUTO ALEXANDER FLEMING; Hospita l Central del IPS; INSTITUTO DE PATOLOGIA E IMUNOLOGIA MOLECULAR DA UNIVERSIDADE DO PORTO PCUP Not yet recruiting