Why Bringing Back DDT to Fight Zika Mosquitoes Could Backfire

MoreWHO Says Further Investigation Needed on Sexual Transmission of ZikaSee All the Places Where the Zika Virus Has Spread Less than a century since DDT was first sprayed, the spread of the Zika virus through mosquitoes has left some wondering whether regulators were too quick to move away from the chemical. But public health officials warn returning the controversial pesticide to use could do more harm than good in some places. DDT, which first came into use as an insecticide in the 1930s, played a crucial role helping Allied forces protect themselves from mosquitoes carrying malaria in World World II and eventually helped eliminate the deadly disease from the U.S. But despite its successes, public opinion turned quickly in the 1960s as outrage grew over DDT’s potential risks to human health and animals and many countries joined the U.S. in ultimately banning its use. Today, health officials caution that while the benefits of the pesticide can outweigh health concerns in some contexts, spraying DDT to combat Zika would be premature and potentially very misguided. “It’s a difficult question, and it’s a very controversial question,” says Jonathan Chevrier, an assistant professor at McGill University, of how policymakers weigh the use of DDT to protect public health. “What the Zika virus is potentially doing is terrible. But using any pesticide needs to be considered very, very carefully.” Read More: All the Ways Humans Try to Kill Mosq...
Source: TIME.com: Top Science and Health Stories - Category: Consumer Health News Authors: Tags: Uncategorized Zika Source Type: news

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Publication date: Available online 16 November 2018Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Donatella Feretti, Roberta Pedrazzani, Elisabetta Ceretti, Mario Dal Grande, Ilaria Zerbini, Gaia Claudia Viviana Viola, Umberto Gelatti, Francesco Donato, Claudia ZaniAbstractAir pollution has well-known harmful effects on human beings, causing both acute and chronic diseases. Some data suggest that genetic damage occurring early in life may influence the risk of having cancer and other chronic diseases in adulthood. Therefore, there is a growing interest in studying the genotoxic activit...
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - Category: Genetics & Stem Cells Source Type: research
ConclusionRadium-223 is a valuable therapeutic alternative in the treatment of patients with mCRPC in early stages of the disease, with a good safety profile. Its benefits extend to the bone environment.ResumenContextoEliminar las metástasis óseas, restaurar/preservar la morfología ósea y prevenir/retrasar los eventos óseos constituyen un objetivo fundamental en el manejo del cáncer de próstata resistente a la castración metastásico (CPRCm). Radio-223 es la primera terapia alfa-dirigida con acción sobre el hueso que aumenta la supervivencia en estos paci...
Source: Actas Urologicas Espanolas - Category: Urology & Nephrology Source Type: research
Publication date: December 2018Source: American Journal of Preventive Medicine, Volume 55, Issue 6Author(s):
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Publication date: December 2018Source: American Journal of Preventive Medicine, Volume 55, Issue 6Author(s):
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
This study aimed to review the effect of decision aids on men's screening intention, screening utilization, and the congruence between intentions and uptake.Evidence acquisitionData sources were searched through April 6, 2018, and included MEDLINE, Scopus, CENTRAL, CT.gov, Cochrane report, PsycARTICLES, PsycINFO, and reference lists. This study included RCTs and observational studies of decision aids that measured prostate screening intention or behavior. The analysis was completed in April 2018.Evidence synthesisEighteen studies (13 RCTs, four before–after studies, and one non-RCT) reported data on screening intenti...
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Publication date: December 2018Source: American Journal of Preventive Medicine, Volume 55, Issue 6Author(s):
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Publication date: Available online 16 November 2018Source: The Lancet Respiratory MedicineAuthor(s): Michael A Matthay, Carolyn S Calfee, Hanjing Zhuo, B Taylor Thompson, Jennifer G Wilson, Joseph E Levitt, Angela J Rogers, Jeffrey E Gotts, Jeanine P Wiener-Kronish, Ednan K Bajwa, Michael P Donahoe, Bryan J McVerry, Luis A Ortiz, Matthew Exline, John W Christman, Jason Abbott, Kevin L Delucchi, Lizette Caballero, Melanie McMillan, David H McKennaSummaryBackgroundTreatment with bone-marrow-derived mesenchymal stromal cells (MSCs) has shown benefits in preclinical models of acute respiratory distress syndrome (ARDS). Safety ...
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
In this study we extended the range of stimulation frequencies, using also low and medium stimulation frequencies (4, 6, 8, 12, 20, 40 Hz) and studied their susceptibility to the loss of consciousness in NREM sleep (N2 and N3 stages).Effects of NREM sleep were examined in power domain with relative power (RP), and in phase domain using inter-trial phase coherence (PC) parameter. The activity in power domain was also compared to no-stimulation data. Regions displaying significant waking-NREM sleep differences were selected using non-parametric suprathreshold cluster test. For 4, 6, 20 and 40 Hz stimulation relative powe...
Source: International Journal of Psychophysiology - Category: Psychiatry & Psychology Source Type: research
Publication date: Available online 17 November 2018Source: Pathology - Research and PracticeAuthor(s): Li MaAbstractNeoadjuvant chemotherapy(NCT) has become the standard treatment for breast cancer. The information about the tumor’s sensitivity to chemotherapy and prognostic significance based on response to therapy can be provided after individualized neoadjuvant treatment. The biomarkers are key factors in the decision-making process regarding treatment as well as important prognostic indicators. Studies have shown that patients who achieve pathological complete response(pCR) after NCT have a better prognosis. For ...
Source: Pathology Research and Practice - Category: Pathology Source Type: research
In this study, we generated VLPs containing hemagglutinin (HA), neuraminidase (NA) or M1 proteins derived from the A/California/04/09. Mice were immunized intramuscularly with HA-M1, NA-M1 or M1 VLPs and protective immunity was evaluated by assessing lung virus loads against low (5LD50) or high (100LD50) lethal dose of homologous virus challenges. High levels of virus-specific serum IgG antibody responses were induced in mice after HA-M1 VLPs immunization, whereas low or no IgG antibody responses were detected from immunization with NA-M1 VLPs or M1 VLPs, independently. Mice that were immunized with HA-M1 VLPs showed below...
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
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