Why Bringing Back DDT to Fight Zika Mosquitoes Could Backfire

MoreWHO Says Further Investigation Needed on Sexual Transmission of ZikaSee All the Places Where the Zika Virus Has Spread Less than a century since DDT was first sprayed, the spread of the Zika virus through mosquitoes has left some wondering whether regulators were too quick to move away from the chemical. But public health officials warn returning the controversial pesticide to use could do more harm than good in some places. DDT, which first came into use as an insecticide in the 1930s, played a crucial role helping Allied forces protect themselves from mosquitoes carrying malaria in World World II and eventually helped eliminate the deadly disease from the U.S. But despite its successes, public opinion turned quickly in the 1960s as outrage grew over DDT’s potential risks to human health and animals and many countries joined the U.S. in ultimately banning its use. Today, health officials caution that while the benefits of the pesticide can outweigh health concerns in some contexts, spraying DDT to combat Zika would be premature and potentially very misguided. “It’s a difficult question, and it’s a very controversial question,” says Jonathan Chevrier, an assistant professor at McGill University, of how policymakers weigh the use of DDT to protect public health. “What the Zika virus is potentially doing is terrible. But using any pesticide needs to be considered very, very carefully.” Read More: All the Ways Humans Try to Kill Mosq...
Source: TIME.com: Top Science and Health Stories - Category: Consumer Health News Authors: Tags: Uncategorized Zika Source Type: news

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ConclusionsFOSL1 is an independent prognostic biomarker of GC. Detecting FOSL1 expression could help stratify GC patients with high-risk and guide the precious treatment.
Source: Pathology Research and Practice - Category: Pathology Source Type: research
In this study, we aimed to investigate the role of IL-6/Stat3 signaling pathway in human endometrial cancer cells invasion and migration. We demonstrated that Stat3 is activated in endometrial cancer cell lines. To investigate the role of Stat3 in endometrial cancer invasive capacity, we used Stat3 inhibitor Stattic and found that Stattic significantly inhibited the migration and invasion of endometrial cancer cells elevated by IL-6. Furthermore, we showed that Stat3 inhibitor significantly decreased the expression of MMP2 enhanced by IL-6, indicating that IL-6 promoted endometrial cancer invasion and migration by Stat3-in...
Source: Pathology Research and Practice - Category: Pathology Source Type: research
Publication date: Available online 19 March 2019Source: Pathology - Research and PracticeAuthor(s): Xiaobo He, Ying ShuAbstractIncreasing evidence has shown that dysregulation of mircoRNA (miRNA) is linked to the development and progression of human cancer, including gastric cancer (GC). In the current study, by analysing the GEO database (GSE78091), we found that miR-660 was significantly downregulated in GC. Consistently, quantitative real-time PCR (qRT-PCR) results showed that miR-660 was dramatically decreased in GC tissues and cell lines. Importantly, low miR-660 expression was closely related to larger tumor size (P&...
Source: Pathology Research and Practice - Category: Pathology Source Type: research
ConclusionsThe results pointed out that the high expression of miR-106b-5p serves as an independent factor for predicting the worse prognosis of RCC patients.
Source: Pathology Research and Practice - Category: Pathology Source Type: research
In conclusion, clinical presentation at time of diagnosis of brain metastases consistently includes neurologic signs and symptoms with persistent headache being the most common. Endometrial cancer patients that present with new neurologic complaints or exam findings should be evaluated for brain metastases.
Source: Gynecologic Oncology Reports - Category: OBGYN Source Type: research
This article discusses a quality improvement project across four NP-owned primary care clinics in which all clinical staff received an educational intervention focused on best vaccination practices and Medicare billing strategies. This project yielded improved vaccination rates in the older adult patient population over a 3-month period.
Source: The Nurse Practitioner - Category: Nursing Tags: Feature: PREVENTIVE CARE: DNP SPECIAL ISSUE Source Type: research
In states that legalized medical marijuana, there was a 4.8 percent decrease in reported pain for conditions that qualified for pot treatment (cancer, arthritis, glaucoma and pain), compared to states without medical marijuana.
Source: WebMD Health - Category: Consumer Health News Source Type: news
A new study from the UC San Diego School of Medicine found that pancreatic cancer patients live longer when they have low levels of enzxyme PHLPP1 and high levels of enzyme PKC.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Publication date: Available online 19 March 2019Source: SeizureAuthor(s): Ilaria Lagorio, Federico Zara, Salvatore Striano, Pasquale StrianoAbstractFamilial adult myoclonic epilepsy (FAME), also described with different acronyms (ADCME, BAFME, FEME, FCTE and others), is a high-penetrant autosomal dominant condition featuring cortical hand tremors, myoclonic jerks, and occasional/rare convulsive seizures. Prevalence is unknown since this condition is often under-recognized, but it is estimated to be less than 1/35,000. The disease usually starts in the second decade of life and has been genetically associated with at least ...
Source: Seizure - Category: Neurology Source Type: research
Publication date: May 2019Source: Epilepsy &Behavior, Volume 94Author(s): Ann Hempel, Michael Frost, Nitin AgarwalAbstractFew studies have examined treatment response in electrical status epilepticus in sleep (ESES), and fewer still have evaluated the effect of corticosteroid treatment employing a pulse-dose regimen. The aim of this study was to examine the effectiveness of pulse-dose prednisone in treating language and behavioral disturbances that often accompany ESES. The sample included 17 patients age 5 to 10 years at time of baseline electroencephalogram (EEG) and neuropsychological assessments. For all patients...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
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