Evaluation of role of Notch3 signaling pathway in human lung cancer cells

Conclusion Notch3 signaling in lung carcinoma is dependent on cell type. In SCLC, Notch3 behaves as a tumor suppressor pathway, while in NSCLC it acts as a tumor-promoting pathway.

http://link.springer.com/10.1007/s00432-016-2117-4

Source: Journal of Cancer Research and Clinical Oncology - February 2, 2016 Category: Cancer & Oncology Source Type: research