Randomized Phase III Trial of Standard Therapy Plus Low Molecular Weight Heparin in Patients With Lung Cancer: FRAGMATIC Trial [Thoracic Oncology]
Conclusion
LMWH did not improve overall survival in the patients with lung cancer in this trial. A significant reduction in VTE is associated with an increase in clinically relevant nonmajor bleeding. Strategies to target those at greatest risk of VTE are warranted.
Source: Journal of Clinical Oncology - Category: Cancer & Oncology Authors: Macbeth, Noble, Evans, Ahmed, Cohen, Hood, Knoyle, Linnane, Longo, Moore, Woll, Appel, Dickson, Ferry, Brammer, Griffiths Tags: Supportive Care, Supportive Care, Combined Modality Thoracic Oncology Source Type: research