Relative sensitivity of immunohistochemistry, multiple reaction monitoring mass spectrometry, hybridization and PCR to detect Coxsackievirus B1 in A549 cells

Enterovirus1 (EV) infections are common in all age groups. They are usually asymptomatic or cause only mild respiratory symptoms, but can also lead to more severe illness including hand, foot and mouth disease, myocarditis, meningitis, encephalitis, pancreatitis, systemic infection in newborns and paralysis. EV infections may also play a role in the pathogenesis of chronic diseases such as dilated cardiomyopathy [1], chronic fatigue syndrome [2] and type 1 diabetes2 (T1D) [3–5].
Source: Journal of Clinical Virology - Category: Virology Authors: Source Type: research