What You Need to Know About the Zika Virus

The rapid spread of Zika virus through the Americas, together with the association of infection with microcephaly and Guillain-Barré syndrome, have propelled this previously ignored virus into the limelight. What is this virus and where did it come from? History Zika virus was first identified in 1947 in a sentinel monkey that was being used to monitor for the presence of yellow fever virus in the Zika Forest of Uganda. At this time, cell lines were not available for studying viruses, so serum from the febrile monkey was inoculated intracerebrally into mice. All the mice became sick, and the virus isolated from their brains was called Zika virus. The same virus was subsequently isolated from Aedes africanus mosquitoes in the Zika forest. Serological studies done in the 1950s showed that humans carried antibodies against Zika virus, and the virus was isolated from humans in Nigeria in 1968. Subsequent serological studies revealed evidence of infection in other African countries, including Uganda, Tanzania, Egypt, Central African Republic, Sierra Leone, and Gabon, as well as Asia (India, Malaysia, Philippines, Thailand, Vietnam, Indonesia). Zika virus moved outside of Africa and Asia in 2007 and 2013 with outbreaks in Yap Island and French Polynesia, respectively. The first cases in the Americas were detected in Brazil in May 2015. The virus circulating in Brazil is an Asian genotype, possibly imported during the World Cup of 2014. As of this writing Zika virus has sprea...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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CONCLUSIONS: These OSHAs decreased lifting a resident using human power and taking an unsuitable posture, which are the primary risk factors of LBP. Therefore, these OSHAs should be implemented as priority approaches to prevent LBP among caregivers in care facilities for the elderly. PMID: 31004382 [PubMed - as supplied by publisher]
Source: Journal of Occupational Health - Category: Occupational Health Tags: J Occup Health Source Type: research
Publication date: Available online 20 April 2019Source: PeptidesAuthor(s): Victor J. HrubyAbstractThe current opioid crisis has created a tragic problem in medicine and society. Pain is the most ubiquitous and costly disease in society and yet all of our “treatments” have toxicities, especially for prolonged use. However, there are several alternatives that have been discovered in the past fifteen years that have been demonstrated in animals to have none of the toxicities of current drugs. Many of the compounds are multivalent and have novel biological activity profiles. Unfortunately, none of these have been i...
Source: Peptides - Category: Biochemistry Source Type: research
ConclusionsA high proportion of patients in both groups had pain several years after the second repair. None of the analyses favored Lichtenstein-Lichtenstein, but a few of the secondary outcomes favored Lichtenstein-Laparoscopy.
Source: The American Journal of Surgery - Category: Surgery Source Type: research
Publication date: Available online 20 April 2019Source: Journal of Pediatric Surgery Case ReportsAuthor(s): D.A. Safin, D.V. RomanovAbstractLymphatic malformations (LM) are a congenital malformation of lymphatic vessels. There exist large, small and mixed cystic LMs. Up to the present day, the causes of LM remain the subject of scientific research. Special sclerosing agents such as Doxycycline, Bleocyne, Picibanil (OK-432) and other drugs are used for sclerosing of LM. Due to the special characteristics of the impact of each drug on the endothelium, during the early post-surgical period there occur various undesirable effe...
Source: Journal of Pediatric Surgery Case Reports - Category: Surgery Source Type: research
DEA raids Tempe pain management clinic, 2 arrested Authorities say two employees at a pain management clinic were arrested Thursday in a raid involving federal agents. www.abc15.com "The DEA identified the two suspects Friday as Naturopathic Medical Doctor Jelina Ip and her mother, Alane Ip. The two are accused of over-prescribing controlled substances, including oxycodone and morphine. The Ips face dozens of criminal charges including fraud schemes, illegally conducting an enterprise, illegal administration of a narcotic... DEA Raids Arizona...
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
In conclusion, preterm classical Caesarean section is not associated with significantly increased risks, but data are scarce. Subsequent uterine rupture risk when not planning a trial of labour is 1%. PMID: 31003949 [PubMed - as supplied by publisher]
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
CONCLUSION: Online information on COCs was variable in quality, often missing key information for making informed decisions. Health care providers should be aware of information gaps when advising women to seek information online. PMID: 31003948 [PubMed - as supplied by publisher]
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
AbstractPain management in the pediatric population is complex for many reasons. Mild pain is usually managed quite well with oral acetaminophen or ibuprofen. Situations involving more severe pain often require the use of an opioid, which may be administered by many different routes, depending on clinical necessity. Acute and chronic disease states, as well as the constantly changing maturational process, produce unique challenges at every level of pediatrics in dosing and management of all medications, especially with regard to high-risk opioids. Although there has been significant progress in the understanding of opioid ...
Source: European Journal of Drug Metabolism and Pharmacokinetics - Category: Drugs & Pharmacology Source Type: research
CONCLUSIONS: The assessment of pain, sedation and delirium is demonstrated, and low percentages of agitation and delirium achieved. We observed a high percentage of patients with pain, and moderate use of PC. We should generalise the use of protocols to assess, prevent and treat pain and delirium by appropriately managing analgesia, sedation, and individual and well-considered use of PC. (ClinicalTrials.gov Identifier: NCT03773874). PMID: 31003871 [PubMed - as supplied by publisher]
Source: Enfermeria Intensiva - Category: Nursing Tags: Enferm Intensiva Source Type: research
CONCLUSIONS ZIKV epidemic poses new challenges to public health, our knowledge about this virus is incipient. In Brazil, a relationship between ZIKV and microcephaly has been mentioned since November 20157 which has not been reported in ZIKV outbreaks in other areas of the world. Several research groups are working on this topic. Guillain Barré Syndrome also has been reported as a complication of ZIKV; however, there are still many questions unanswered regarding the complications caused by this virus. Provide information to the population, following recommendations and preventive measures, taking actions to reduce...
Source: PLOS Currents Outbreaks - Category: Epidemiology Authors: Source Type: research
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