National clinical trial to test new treatment for tinnitus
UT Southwestern will take part in a national clinical trial to test a device that could provide relief for people suffering from tinnitus, a persistent buzzing or ringing sound in the ears.
Photomedicine and Laser Surgery, Ahead of Print.
Conclusions: The study shows that the hippocampus is excited in SA-induced tinnitus, and stimulation of hippocampus could modulate neuronal excitability of the AC. The hippocampus is involved in tinnitus and may also have a regulatory effect on the neural center. PMID: 30082529 [PubMed - in process]
Condition: Tinnitus Interventions: Device: Sham then Active; Device: Active then Sham Sponsors: University of Michigan; National Institute of Mental Health (NIMH) Recruiting
CONCLUSION: Transmastoid clipping of a sigmoid sinus diverticulum can be a safe and effective method of managing pulsatile tinnitus resulting from a sigmoid sinus diverticulum. PMID: 30078382 [PubMed - as supplied by publisher]
CONCLUSIONS: S-SNHL can be an early manifestation of MS and should always be considered in the differential diagnosis of this condition, especially in women. The pathophysiology can be explained by the involvement of microglia attacking the central and/or peripheral auditory pathways as indicated by WMHs. PMID: 30058696 [PubMed - in process]
Conclusion: Tympanic membrane perforation arises mainly from middle ear infections and traumatic causes. At presentation, size and location of perforation vary which depend on duration of infection or the traumatic causes.
This randomized clinical trial investigates whether inhaled nitrous oxide and oxygen vs inhaled nitrogen and oxygen can reduce bothersome tinnitus among adults with subjective, idiopathic, nonpulsatile tinnitus of 6 months ’ duration or longer.
Publication date: Available online 31 July 2018Source: Neuroscience LettersAuthor(s): Jeffrey Hullfish, Ian Abenes, Silvia Kovacs, Stefan Sunaert, Dirk De Ridder, Sven VannesteAbstractBayesian models of brain function such as active inference and predictive coding offer a general theoretical framework with which to explain several aspects of normal and disordered brain function. Of particular interest to the present study is the potential for such models to explain the pathology of auditory phantom perception, i.e. tinnitus. To test this framework empirically, we perform an fMRI experiment on a large clinical sample (n&thi...
Conclusion: Stent-adjacent stenosis is an important complication following venous stenting in patients with DVSS and IIH. Further studies are needed to identify determinants of stent-adjacent stenosis and stent nonsurvival.Intervent Neurol 2018;7:490 –500