Virulence and antimicrobial resistance of Klebsiella pneumoniae isolated from passerines and psittacine virds.

Virulence and antimicrobial resistance of Klebsiella pneumoniae isolated from passerines and psittacine virds. Avian Pathol. 2016 Jan 26;:1-28 Authors: Davies YM, Cunha MP, Oliveira MG, Oliveira MC, Philadelpho N, Romeiro DC, Milanelo L, Guimarães MB, Ferreira AJ, Moreno AM, Sá LR, Knöbl T Abstract Klebsiella pneumoniae is considered one of the most important Gram-negative opportunistic pathogens. The contact between humans and birds poses health risks to both. The aim of this study was to investigate the resistance and virulence of K. pneumoniae isolates from psittacines and passerines, seized from illegal trade in Brazil. We analyzed 32 strains isolated from birds of the orders Psittaciformes and Passeriformes by Polymerase Chain Reaction (PCR) for virulence factor genes. Antibiotic resistance was assessed by disk diffusion assay and PCR. The results indicated that fimH (100%), uge (96.8%), kfu (81.2%) and irp-2 (68.7%) were the most common virulence genes, followed by kpn (46.8%), K2 (43.7%), mrkD (34.3%), and iroN (15.6%). The combination of virulence genes resulted in a great diversity of genotypes and the heterogeneity of the strains is also confirmed in the analysis by AFLP. The susceptibility profiles of the K. pneumoniae showed 25% of multiple antibiotic resistance strains. We identified seven strains that presented non-ESBL blaSHV variants SHV-1 and SHV-11 and one strain positive to the blaTEM-1 gene. Plasmid-mediated quinolo...
Source: Avian Pathology - Category: Pathology Authors: Tags: Avian Pathol Source Type: research

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