Investigation of Somatic GNAQ, GNA11, BAP1 and SF3B1 Mutations in Ophthalmic Melanocytomas

Conclusions: The presence of GNAQ mutation in some iridociliary and optic-nerve melanocytomas suggests a possible relationship between ophthalmic melanocytoma and other ophthalmic melanocytic neoplasms. BAP1 mutation may accompany the transformation of ophthalmic melanocytoma to melanoma.Ocul Oncol Pathol 2016;2:171-177

http://www.karger.com/Article/FullText/442352

Source: Ocular Oncology and Pathology - January 27, 2016 Category: Opthalmology Source Type: research