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Thyroid or Treats: What's Really Preventing You From Losing Weight

Have you been eating healthy, avoiding sugar, going to the gym but still struggling to lose weight? If that's the case, you might want to think about getting your thyroid checked. Your thyroid plays an important part in regulating your metabolism and can affect your ability to lose weight. So, if you find yourself struggling to squeeze into your favorite pair of jeans despite following your New Year's resolution, stop thinking it's' your fault and instead find out if something else might be going on with that small butterfly-shaped gland in front of your windpipe. Patients often seem surprised when I say there might be something wrong with their thyroid. Thyroid disease is actually a lot more common than you may think. In fact, an estimated 20 million Americans have some form of thyroid disease, and more than half are unaware of it. And if you're a woman -pay close attention: Women are actually eight times more likely to have thyroid problems than men. And if you're a woman over the age of 60? Your chances almost triple compared to your younger counterparts. Your thyroid can be overactive or underactive. An underactive thyroid - known as hypothyroidism --- may make it difficult to drop a dress size, but problems losing weight isn't the only symptom. There are several other important symptoms to be aware of. What should you be on the lookout for? In addition to the commonly associated weight gain, thinning hair can be a noticeable sign - and one that is often ignored. If you ...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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Authors: Zang H, Jiang F, Cheng X, Xu H, Hu X Abstract Adropin has been identified as potent regulatory hormone implicated in insulin sensitivity and the maintenance of energy homeostasis. The aim of current study was to investigate serum adropin concentrations of type 2 diabetes mellitus (T2DM) patients in the fasting status, especially those overweight/obese and evaluate the relationships between adropin levels and metabolic parameters. A total of 116 T2DM patients and 60 controls with normal glucose tolerance (NGT) were recruited to the study. Adropin concentration was determined using commercial ELISA kits. Ant...
Source: Endocrine Journal - Category: Endocrinology Tags: Endocr J Source Type: research
CONCLUSIONS: We report a rare case of TERT, HRAS, and EIF1AX mutations in a patient with follicular adenoma. TERT promoter mutations may be an early genetic event in the molecular pathogenesis of follicular thyroid carcinoma. PMID: 29669480 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
We present the case of a 68-year-old woman with combined antiphospholipid syndrome and factor XI deficiency, with chronic prolongation of activated partial thromboplastin time that was not correctable with fresh-frozen plasma (FFP).The patient had a history of stroke, but was not on antiplatelet therapy because of mucocutaneous bleeding events. She had progressive renal failure attributed to her autoimmune disease, and a decision was made to pursue peritoneal dialysis (PD) when she reached end-stage kidney disease. She was admitted to the hospital the day before her planned PD catheter placement and was transfused with FFP...
Source: Advances in Peritoneal Dialysis. Conference on Peritoneal Dialysis - Category: Urology & Nephrology Tags: Adv Perit Dial Source Type: research
Conclusion Our results suggest that control of lipid levels in patients with FH has improved and that the achievement of guideline-directed goals has been facilitated by access to PCSK9 inhibitors. These observations provide insight into the real-world effectiveness of PCSK9 inhibitor therapy in patients with FH. Teaser Familial Hypercholesterolemia (FH) is characterized by very high levels of low density lipoprotein cholesterol and increased risk of cardiovascular events. We examined the real-world impact of PCSK9 inhibitors on lipid levels in patients in the British Columbia FH Registry. From 2015 to 2017, lipid levels i...
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
AbstractPurposeThe purpose of this study was to investigate whether a treadmill endurance exercise program would reduce serum testosterone and leptin in male rats and assess the impact of increased dietary cholesterol on serum hormones.MethodsMale Sprague-Dawley Rats (n = 20) were randomly assigned to a control group (C) or an exercise training group (EX) that performed treadmill running 40 min/day, 6 days/week for 12 weeks. At study midpoint (week 6), rats were randomized to a high-cholesterol (HC) diet (n = 10) or remain on standard semi-purified (LC) diet (n = ...
Source: Sport Sciences for Health - Category: Sports Medicine Source Type: research
AbstractPurpose of ReviewThis review summarizes the recent epidemiologic literature examining environmental exposures and health outcomes in rural, minority populations in the southwestern and mountain west region of the USA identifying areas requiring further data and research.Recent FindingsRecent studies (2012 –2017) in this region have primarily focused on arsenic exposure (n = 10 studies) with similar results reported across populations in this region. Associations between arsenic and cadmium were reported for cardiovascular and kidney disease, type II diabetes, cognitive function, hypothyroidism, an...
Source: Current Epidemiology Reports - Category: Epidemiology Source Type: research
The finding by Remmler et  al1 that increased levels of interleukin 6 (IL6) predict 90-day and 1-year mortality in patients with end-stage liver disease is of high importance. In addition to its relevance for prognosis and timing of liver transplantation, we believe that the determination of IL6 levels could represent a pos sible target for therapy. Indeed, IL6 increases occur in autoimmune diseases, but more importantly is a consequence of infections. Viral causes of chronic liver diseases, such as hepatitis C and B viruses, now can be cured in a very high percentage of patients with the administration of antivirals.
Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Tags: Letter to the Editor Source Type: research
Authors: Somfai GM, Gerding H, DeBuc DC Abstract Diabetic retinopathy (DR) is one of the leading causes of vision loss globally with a severe burden on all societies due to its high treatment and rehabilitation costs. The early diagnosis of DR may provide preventive steps (including retinal laser therapy and tight carbohydrate, blood pressure, and cholesterol control) that could in turn help to avoid progression of the pathology with the resultant vision loss. Optical coherence tomography (OCT) enables the in vivo structural imaging of the retina, providing both qualitative (structure) and quantitative (thickness) ...
Source: Klinische Monatsblatter fur Augenheilkunde - Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research
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Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Medscape Today News Source Type: news
Authors: Jalloh MA, Ip EJ, Doroudgar S Abstract INTRODUCTION: In 2017, Schmidt et al. conducted a Cochrane systematic review and meta-analysis to evaluate the effect of using proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors to reduce low-density-lipoprotein- cholesterol (LDL-C) and cardiovascular disease (CVD). The Cochrane review was a systematic review and meta-analysis of 20 randomized, double-blinded trials that compared the use of PCSK9 inhibitors with statins/ezetimibe, ezetimibe, or placebo for a treatment duration of at least 24 weeks. The use of PCSK9 inhibitors lowered the risk for CVD (OR...
Source: Expert Opinion on Pharmacotherapy - Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
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