Lack of an Effect of Ritonavir Alone and Lopinavir‐Ritonavir on the Pharmacokinetics of Fenofibric Acid in Healthy Volunteers

ConclusionIn contrast to a significant interaction between gemfibrozil and lopinavir‐ritonavir, neither lopinavir‐ritonavir nor ritonavir alone altered the pharmacokinetics of fenofibric acid in healthy volunteers. These data suggest that fenofibrate remains an important option in human immunodeficiency virus–infected patients receiving common ritonavir‐boosted therapy.

Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - January 21, 2016 Category: Drugs & Pharmacology Authors: Lori A. Gordon, Christine Y. Malati, Colleen Hadigan, Mary McLaughlin, Raul M. Alfaro, Mónica M. Calderón, Joseph A. Kovacs, Scott R. Penzak Tags: Original Research Article Source Type: research