Myeloid cell-derived LRG attenuates adverse cardiac remodelling after myocardial infarction

Conclusion
LRG, produced by heart-infiltrating myeloid cells, suppresses adverse cardiac remodelling after MI as a novel cardioprotective factor. LRG signalling could be a therapeutic target against cardiovascular diseases.

Source: Cardiovascular Research - January 25, 2016 Category: Cardiology Authors: Kumagai, S., Nakayama, H., Fujimoto, M., Honda, H., Serada, S., Ishibashi-Ueda, H., Kasai, A., Obana, M., Sakata, Y., Sawa, Y., Fujio, Y., Naka, T. Tags: Cardiac biology and remodelling Source Type: research