IgA nephropathy and infections.

IgA nephropathy and infections.
J Nephrol. 2016 Jan 22;
Authors: Rollino C, Vischini G, Coppo R
Abstract
In this paper we concentrate on the role of infections in IgA nephropathy both from a pathogenetic and clinic point of view. The current hypotheses as regards the role of infections in the pathogenesis of IgA nephropathy are: (a) role of particular pathogens, (b) chronic exposure to mucosal infections, (c) abnormal handling of commensal microbes (gut microbiota). We also focus on particular infections reported in association with classic IgA nephropathy (HIV, malaria, Chlamydia, Lyme disease), as well as on IgA dominant-infection-associated glomerulonephritis. This is a unique form of glomerulonephritis, where IgA deposition is dominant. It is mostly recognized in old, diabetic patients and in association with staphylococcal infection.
PMID: 26800970 [PubMed - as supplied by publisher]

Source: Journal of Nephrology - January 22, 2016 Category: Urology & Nephrology Authors: Rollino C, Vischini G, Coppo R Tags: J Nephrol Source Type: research